Membrane phospholipid fatty acid composition regulates cardiac SERCA activity in a hibernator, the Syrian hamster (Mesocricetus auratus). [PDF]
Polyunsaturated fatty acids (PUFA) have strong effects on hibernation and daily torpor. Increased dietary uptake of PUFA of the n-6 class, particularly of Linoleic acid (LA, C18:2 n-6) lengthens torpor bout duration and enables animals to reach lower ...
Sylvain Giroud +5 more
doaj +1 more source
Mitochondrial polymorphism m.3017C>T of SHLP6 relates to heterothermy
Heterothermic thermoregulation requires intricate regulation of metabolic rate and activation of pro-survival factors. Eliciting these responses and coordinating the necessary energy shifts likely involves retrograde signalling by mitochondrial-derived ...
Sarah V. Emser +5 more
doaj +1 more source
The grey mouse lemur uses season-dependent fat or protein sparing strategies to face chronic food restriction. [PDF]
During moderate calorie restriction (CR) the heterotherm Microcebus murinus is able to maintain a stable energy balance whatever the season, even if only wintering animals enter into torpor.
Sylvain Giroud +10 more
doaj +1 more source
Seasonal and fasting induced changes in iron metabolism in Djungarian hamsters.
Djungarian hamsters are small rodents that show pronounced physiological acclimations in response to changes in photoperiod, and unfavorable environmental conditions such as reduced food availability and low external temperature.
Rawan Kawach +5 more
doaj +1 more source
Heart rate reveals torpor at high body temperatures in lowland tropical free-tailed bats [PDF]
Reduction in metabolic rate and body temperature is a common strategy for small endotherms to save energy. The daily reduction in metabolic rate and heterothermy, or torpor, is particularly pronounced in regions with a large variation in daily ambient ...
M. Teague O'Mara +5 more
doaj +1 more source
The gray mouse lemur (Microcebus murinus) is one of few primate species that is able to enter daily torpor or prolonged hibernation in response to environmental stresses.
Jing Zhang +6 more
doaj +1 more source
Performance of bat-derived macrophages at different temperatures
Heterothermy, as a temperature-dependent physiological continuum, may affect host-pathogen interactions through modulation of immune responses. Here, we evaluated proliferation and functional performance of a macrophage cell line established from the ...
Monika Nemcova +8 more
doaj +1 more source
Mitochondrial metabolism in hibernation and daily torpor: a review
Hibernation and daily torpor involve substantial decreases in body temperature and metabolic rate, allowing birds and mammals to cope with cold environments and/or limited food. Regulated suppression of mitochondrial metabolism probably contributes to energy savings: state 3 (phosphorylating) respiration is lower in liver mitochondria isolated from ...
Staples, James F, Brown, Jason C L
openaire +3 more sources
Daily Torpor in Birds and Mammals: Past, Present, and Future of the Field
Synopsis Torpor is an incredibly efficient energy-saving strategy that many endothermic birds and mammals use to save energy by lowering their metabolic rates, heart rates, and typically body temperatures. Over the last few decades, the study of daily torpor—in which torpor is used for <24 h per bout—has advanced rapidly.
Anusha Shankar +9 more
openaire +3 more sources
Mitochondrial Targeting against Alzheimer’s Disease: Lessons from Hibernation
Alzheimer’s disease (AD) is the most common cause of dementia worldwide and yet remains without effective therapy. Amongst the many proposed causes of AD, the mitochondrial cascade hypothesis is gaining attention.
Christina F. de Veij Mestdagh +3 more
doaj +1 more source

