Results 191 to 200 of about 1,281,664 (278)

The multiple hit model of infantile and epileptic spasms: The 2025 update

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou   +6 more
wiley   +1 more source

Adaptive multihazard modeling predicts rainfall-driven dam failure: a case study. [PDF]

open access: yesSci Rep
Nasser M   +4 more
europepmc   +1 more source

Ketogenic diet for infantile epileptic spasms

open access: yesEpilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury   +3 more
wiley   +1 more source

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

open access: yesEpilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson   +2 more
wiley   +1 more source

Three‐Dimensional Analytical Model of a Free‐Standing Square Rocking Column

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT A three‐dimensional analytical two‐degree‐of‐freedom (2DOF) model is developed to describe the bounded rocking response of free‐standing rigid square columns subjected to bidirectional seismic excitation. The formulation extends Housner's classical planar theory by deriving the full three‐dimensional equations of motion for a column ...
Dimitra Adamopoulou   +1 more
wiley   +1 more source

Evaluation of the Adequacy of Design Specifications for Nonstructural Components in a Reticular Structure

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Nonstructural components (NSCs) installed in large‐span reticular structures were frequently severely damaged during earthquakes, even when the primary structure remained intact. Existing seismic design specifications for NSCs were predominantly developed for upright structures such as multi‐storey buildings and offer no guidance for reticular
Xudong Zhi   +6 more
wiley   +1 more source

Distinct changes in riparian sediment microbial communities with depth and time since dam removal. [PDF]

open access: yesSci Rep
Moore ER   +8 more
europepmc   +1 more source

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