Results 221 to 230 of about 367,573 (256)

The multiple hit model of infantile and epileptic spasms: The 2025 update

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou   +6 more
wiley   +1 more source

Ketogenic diet for infantile epileptic spasms

open access: yesEpilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury   +3 more
wiley   +1 more source

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

open access: yesEpilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson   +2 more
wiley   +1 more source

Perceptions of plastic pollution among inland fishery stakeholders in a subtropical reservoir. [PDF]

open access: yesPLoS One
Murungweni FM   +5 more
europepmc   +1 more source

Three‐Dimensional Analytical Model of a Podium Structure With Rocking Columns of Square Cross Section

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Allowing structural systems to uplift and rock during seismic excitation has emerged as an effective and inherently self‑centering form of seismic isolation. This paper develops a computationally efficient 3D analytical model suitable for the understanding of the behavior of rocking bridges.
Dimitra Adamopoulou   +1 more
wiley   +1 more source

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