Results 41 to 50 of about 6,565,441 (278)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Regional differences in health exposure risk of indoor benzene series and safety threshold determination for the Chinese population

Ecotoxicology and Environmental Safety
Indoor benzene series (BTEX) pollution from building and decoration materials poses growing health risks during China's urbanization. Nationwide multi-scenario exposure assessments remain limited, and the risk-based thresholds for benzene and ...
Xuepu Ma, You Li, Xiaoyong Liao, Liang Wang, Huan Tao, Hongying Cao   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An integrated approach for determining the spatial distribution, source apportionment and human health risks of PAHs in soils of rapidly-urbanized areas

Soil & Environmental Health
The rise of large urban agglomerations has exacerbated pollutant emissions, resulting in regional soil contamination with polycyclic aromatic hydrocarbons (PAHs), which jeopardizes the development of urban agglomerations and affects human health.
Lingzhi Luo, Xiaoyong Liao, Huan Tao, You Li, Liang Wang, Hongying Cao, Yonghua Li, Weiwei Shi, Tianyi Wang   +8 more
doaj   +1 more source

Development and Application of the Real-Time Individual Asset Attribute Collection Tool

Frontiers in Built Environment, 2019
Rapid and profound changes in the technology used for data acquisition, computing and information management provides a framework that has the potential to allow communities to consider acquiring, analyzing and managing data in new ways.
Sheng-Lin Lin, Andrew King, Nick Horspool, Vinod Sadashiva, Ryan Paulik, Shaun Williams   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Identification of damage in composite materials using thermoelastic stress analysis

, 2007
A quantitative damage assessment methodology for composite materials has beenachieved using Thermoelastic Stress Analysis (TSA). The TSA technique provides fullfielddata which is collected in a non-contacting and real time manner.
Emery, Trystan Ross
core   +1 more source

Urban-rural inequality in soil heavy metal health risks: Insights from Baoding, China

Ecotoxicology and Environmental Safety
Soil heavy metal contamination poses serious health risks, but few studies have quantitatively assessed disparities in these risks between urban and rural populations.
Lingzhi Luo, Liang Wang, You Li, Hongying Cao, Yanling Guo, Xiaoyong Liao   +5 more
doaj   +1 more source

Failure Monitoring and Condition Assessment of Steel-Concrete Adhesive Connection Using Ultrasonic Waves

Applied Sciences, 2018
Adhesive bonding is increasingly being incorporated into civil engineering applications. Recently, the use of structural adhesives in steel-concrete composite systems is of particular interest. The aim of the study is an experimental investigation of the
Magdalena Rucka
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source