Results 41 to 50 of about 3,928,621 (275)

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

Impact assessment of biodiesel production using CaO catalyst obtained from two different sources

Cogent Engineering, 2019
In this research work, the comparative analysis of the production of high yield and environmental friendly biodiesel obtained from the transesterification of waste soybean oil, using technical grade CaO catalyst and CaO catalyst derived from chicken ...
A.A. Ayoola, O.S.I. Fayomi, O.A. Adeeyo, J.O. Omodara, O. Adegbite   +4 more
doaj   +1 more source

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

Characterization of the role of Fhit in suppression of DNA damage [PDF]

Advances in Biological Regulation, 2013
The fragile histidine triad protein, Fhit, has a number of reported tumor suppressive functions which include signaling of apoptosis in cancer cells in vitro and in vivo, modulation of the DNA damage response, down-regulation of target oncogene expression, suppression of tumor growth in vivo, and suppression of cancer cell invasion and metastasis. Most
Joshua C, Saldivar, Jessica, Bene, Seyed Ali, Hosseini, Satoshi, Miuma, Susan, Horton, Nyla A, Heerema, Kay, Huebner   +6 more
openaire   +2 more sources

Characterization of Properties and Damage in Piezoelectrics [PDF]

, 2010
The aim of this chapter is to review the state of the art of the possibilities and existing knowledge on characterization of mechanical and coupling properties and damage detection in piezoelectric ceramics. To address the theoretical problem with a proper rational basis, a review of numerical and experimental techniques to solve the so-called inverse ...
Guillermo Rus, Roberto Palma, Javier Surez   +2 more
openaire   +1 more source

Functional characterization of the TERRA transcriptome at damaged telomeres [PDF]

Nature Communications, 2014
Telomere deprotection occurs during tumorigenesis and aging upon telomere shortening or loss of the telomeric shelterin component TRF2. Deprotected telomeres undergo changes in chromatin structure and elicit a DNA damage response (DDR) that leads to cellular senescence.
Porro Antonio, Feuerhahn Sascha, Delafontaine Julien, Riethman Harold, Rougemont Jacques, Lingner Joachim   +5 more
openaire   +3 more sources

Damage investigation in CFRP composites using full-field measurement techniques: combination of digital image stereo-correlation, infrared thermography and X-ray tomography [PDF]

, 2013
The present work is devoted to damaging process in carbon–fiber reinforced laminated composites. An original experimental approach combining three optical measurement techniques is presented.
Péronnet, Elodie, Welemane, Hélène, Garnier, Christian, Fazzini, Marina, Brault, Romain, Mistou, Sébastien, Goidescu, Cristina   +6 more
core   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source