Results 171 to 180 of about 936,745 (311)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Tikhonov’s Regularization Approach in Mode Shape Curvature Analysis Applied to Damage Detection

In this paper an on-going research effort aimed at detecting and localizing damage in plate-like structuresby using mode shape curvature based damage detection algorithm is described.
Ručevskis, Sandris, Sumbatyan, Mezhlum A., Čate, Andris, Akišins, Pāvels   +3 more
core  

Structural Damage Detection in Real Time: Implementation of 1D Convolutional Neural Networks for SHM Applications

, 2017
Most of the classical structural damage detection systems involve two processes, feature extraction and feature classification. Usually, the feature extraction process requires large computational effort which prevent the application of the classical ...
Abdeljaber, Osama,, Avci, Onur,, Kiranyaz, Serkan,, Inman, Daniel,   +3 more
core  

Corn Kernel Segmentation and Damage Detection Using a Hybrid Watershed-Convex Hull Approach. [PDF]

Foods
Shen Y, Wang W, Luo X, Zou F, Yin Z.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Research on conveyor belt damage detection method based on FDEP-YOLOv8. [PDF]

Sci Rep
Yuan Y, Bai Y, Meng W, Zhou L, Wang M, Qu W.   +5 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Kissing Bond Damage Detection Based on the Non-Reciprocity of Nonlinear Guided Waves in CFRP-Reinforced Steel Plates. [PDF]

Materials (Basel)
Guan R, Zhang H, Deng J, Kang Q, Wang K.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Garlic-YOLO-DD: a lightweight object detection algorithm for garlic damage detection. [PDF]

Front Plant Sci
Gao Y, Ma X, Xia Z, Qi T, Wang X, He Z, Chen G.   +6 more
europepmc   +1 more source