Results 111 to 120 of about 852,434 (310)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Subsoil Compaction as a Climate Damage Indicator [PDF]

open access: yesACS - Agriculturae conspectus scientificus, 2009
Some forms of soil compaction occur on arable lands both in Hungary (1.82 million ha) and in Croatia (0.97 million ha) having negative impacts on agricultural production. Tillage-induced subsoil compaction has often occurred in the Pannonian region in relation to traffic-induced compaction.
Kisić, Ivica, Mesić, Milan
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Convolution Neural Network Development for Identifying Damage in Vibrating Pylons with Mass Attachments

open access: yesSensors
A convolution neural network (CNN) is developed in this work to detect damage in pylons by measuring their vibratory response. More specifically, damage detection through testing relies on the development of damage-sensitive indicators, which are then ...
George D. Manolis, Georgios I. Dadoulis
doaj   +1 more source

Brain asymmetries related to language with emphasis on entorhinal cortex and basal forebrain [PDF]

open access: yes, 2006
Anatomical asymmetries of the human brain are important in at least four respects: 1) they can serve as potential indicators of the evolutionary foundations of language, 2) they can be used for comparative analysis of neural specializations for ...
Hof, Patrick R.   +3 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

REDUCING TRANSPORTATION DAMAGE TO GRAPES AND STRAWBERRIES [PDF]

open access: yes
In-transit vibration damage to grapes and strawberries results in reduced quality for the consumer and reduced profits for the produce industry. To solve this problem, the first step is to determine which vibrational frequencies are causing the damage ...
Ashby, B. Hunt   +2 more
core   +1 more source

Mussel eggs as indicators of mutagen exposure in coastal and estuarine environments [PDF]

open access: yes, 1994
The aim of this study was to develop a short-term genotoxicity assay for monitoring the marine environment for mutagens. Based on the developing eggs and embryos of the marine mussel Mytilus edulis, an important pollution indicator species, the test ...
Dixon, D.R., Pascoe, P.L
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Monitoring and Evaluating the Damage to Shear Connectors in Steel–Concrete Composite Beams by Curvature-Based Indicators Through Vibration Tests

open access: yesApplied Sciences
In order to assess the workability of shearing connectors of steel–concrete composite beams (SCCBs), this manuscript proposed a novel solid-slipping nonlinear finite element (FE) model, which is independent of stiffness-slip function for simply supported
Haobo Zhang, Fangzhu Du, Haoran Jin
doaj   +1 more source

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