Results 141 to 150 of about 1,297,977 (267)

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Water-induced damage mechanism and dual-radius grouting control of weakly cemented argillaceous roadways in Western China. [PDF]

Sci Rep
Yu Z, Lun Z, Zhang Z, Zhang W, Wang S, Zhao L, Liu S.   +6 more
europepmc   +1 more source

Identification of NOL-Ring Composite Materials' Damage Mechanism Based on the STOA-VMD Algorithm. [PDF]

Polymers (Basel), 2023
Jiang P, Li H, Yan X, Zhang L, Li W.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Study on Damage Mechanism of Fiber Concrete with Initial Pores. [PDF]

Materials (Basel)
Hu A, Du X, Wang F, Li J, Zhang T, Li Y.
europepmc   +1 more source

Damage Mechanism of HgCdTe Focal Plane Array Detector Irradiated Using Mid-Infrared Pulse Laser. [PDF]

Sensors (Basel), 2023
Zhang Y, Zheng C, Liu Y, Wang Y, Xu Y, Shao J.   +5 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Damage Mechanism and Modeling of CFRP Laminates Impacted by Single Waterjets: Effect of the Impact Direction. [PDF]

Materials (Basel)
Hou N, Li Y, Liu P.
europepmc   +1 more source

In vitro investigation of stone ablation efficiency, char formation, spark generation, and damage mechanism produced by thulium fiber laser. [PDF]

Urolithiasis, 2023
Chen J, Mishra A, Medairos R, Antonelli J, Preminger GM, Lipkin ME, Zhong P.   +6 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source