Results 51 to 60 of about 6,461,546 (275)
工程科学与技术, 2022 To investigate the damage mechanism of the thick coating in the steel frames under earthquake, one small-scale experiment was conducted. The failure modes and positions of the thick coating in the steel beam and columns were observed in detail. The inter-
Canghu QIU +3 more
doaj
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
BuildingsAs a long lifeline system of buried structures, the utility tunnel (UT) is vulnerable to earthquake invasion. For utility tunnels with inverted siphon arrangements crossing rivers, the seismic response is more complex due to the basin effect of ...
Yuanhong Wang +4 more
doaj +1 more source
Mechanisms of Toxic Damage to Spermatogenesis [PDF]
Journal of the National Cancer Institute Monographs, 2005 Azoospermia and long-lasting testicular atrophy are common adverse consequences of cancer treatment. Chemotherapeutic agents may disrupt spermatogenesis by targeting various testicular cell types (Leydig cells, Sertoli cells, and germ cells) and by activating numerous molecular pathways involved in germ cell life-and-death decision making.
openaire +2 more sources
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microstructure and fatigue damage mechanism of 6082-T6 aluminium alloy welded joint
Materials Research Express, 2021 In this paper, 6mm thick 6082-T6 high-strength aluminium alloy is taken as the research object, and CLOOS ROMAT-3500 industrial robot MIG welder is used for welding.
Minqi Zhu +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Thermal-induced damage mechanisms and permeability evolution in gneiss for deep mining applications
Frontiers in Earth ScienceWith the rapid development of deep mining and geothermal exploitation, the influence of high-temperature environment on the mechanical properties of rocks has become a core challenge for engineering safety.
Jian Zhang +4 more
doaj +1 more source
Study on flexural properties of coal gangue powder asphalt mixture under freeze-thaw cycles
Materials Research Express, 2022 In order to study the influence of freeze-thaw cycle on the flexural performance of asphalt pavement, semi-circular flexural test (SCB) is carried out.
Jinrong Wu +3 more
doaj +1 more source