Results 151 to 160 of about 6,461,546 (275)

Identification of NOL-Ring Composite Materials' Damage Mechanism Based on the STOA-VMD Algorithm. [PDF]

Polymers (Basel), 2023
Jiang P, Li H, Yan X, Zhang L, Li W.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Water-induced damage mechanism and dual-radius grouting control of weakly cemented argillaceous roadways in Western China. [PDF]

Sci Rep
Yu Z, Lun Z, Zhang Z, Zhang W, Wang S, Zhao L, Liu S.   +6 more
europepmc   +1 more source

Damage Mechanism of HgCdTe Focal Plane Array Detector Irradiated Using Mid-Infrared Pulse Laser. [PDF]

Sensors (Basel), 2023
Zhang Y, Zheng C, Liu Y, Wang Y, Xu Y, Shao J.   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Damage Mechanism and Modeling of CFRP Laminates Impacted by Single Waterjets: Effect of the Impact Direction. [PDF]

Materials (Basel)
Hou N, Li Y, Liu P.
europepmc   +1 more source

In vitro investigation of stone ablation efficiency, char formation, spark generation, and damage mechanism produced by thulium fiber laser. [PDF]

Urolithiasis, 2023
Chen J, Mishra A, Medairos R, Antonelli J, Preminger GM, Lipkin ME, Zhong P.   +6 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Strength hardening and damage mechanism of semiwetted coal under cyclic loads with different initial stress levels. [PDF]

Sci Rep
Lv F, Zhang Y, Kong F, Li X, Zou Q.
europepmc   +1 more source

Pyroptosis-Mediated Damage Mechanism by Deoxynivalenol in Porcine Small Intestinal Epithelial Cells. [PDF]

Toxins (Basel), 2023
Kang TH, Shin S, Park J, Lee BR, Lee SI.
europepmc   +1 more source