Results 51 to 60 of about 2,596,701 (301)

Calculation of The Lifetimes of Thin Stripper Targets Under Bombardment of Intense Pulsed Ions

, 2007
The problems of stripper target behavior in the nonstationary intense particle beams are considered. The historical sketch of studying of radiation damage failure of carbon targets under ion bombardment is presented.
A. S. Lebedev, D. V. Fedoseev, J. Yntema, J. E. Field, S. G. Lebedev, V. N. Korobenko, Ya. Groshkovsky   +6 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Crosslinking effect on the deformation and fracture of monodisperse polystyrene-co-divinylbenzene particles

eXPRESS Polymer Letters, 2013
This study focuses on the effect of crosslinking density on the mechanical response of polystyrene-co-divinylbenzene (PS-DVB) particles under compression by means of nanoindentation-based flat punch method combined with SEM observation of particle ...
Z. L. Zhang, J. Y. He, H. Kristiansen, K. Redford, G. Fonnum, G. I. Modahl   +5 more
doaj   +1 more source

Study on mechanical properties and microscopic damage mechanism of tight sandstone reservoir under uniaxial compression

Frontiers in Energy Research, 2023
Due to the characteristics of low porosity, low permeability and serious anisotropy in tight reservoirs, it is difficult for conventional hydraulic fracturing theory to accurately guide the efficient exploitation of tight reservoirs.
Jin Huang, Jiacheng Xing, Xingchuan Liao, Xingchuan Liao, Yixing Ren, Keer Ding, Jin Tan   +6 more
doaj   +1 more source

Nanoscale damage during fracture in silica glass [PDF]

, 2006
We report here atomic force microscopy experiments designed to uncover the nature of failure mechanisms occuring within the process zone at the tip of a crack propagating into a silica glass specimen under stress corrosion.
Bonamy, Daniel, Bouchaud, Elisabeth, Dalmas, Davy, Guillot, Claude, Ponson, Laurent, Prades, Silke, Ravi-Chandar, K., Rountree, Cindy   +7 more
core   +2 more sources

Mechanical Chondrocyte Damage Thresholds

ASME 2012 Summer Bioengineering Conference, Parts A and B, 2012
Chondrocyte content in articular cartilage is very low. Only 2% to 5% of the tissue volume consists of chondrocytes [1]. Yet, these cells are responsible for maintenance of the tissue. Hence, the loss of chondrocytes that is often occurring at an early stage of cartilage degeneration is detrimental to articular cartilage.
Turnhout, van, M.C., Vries, de, S.A.H., Donkelaar, van, C.C., Oomens, C.W.J.   +3 more
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Analyzing the characteristics of the cavity nucleation, growth and coalescence mechanism of 9Cr-1Mo-VNb steel (P91) steel [PDF]

, 2013
Creep damage is one of the serious problems for the high temperature industries and computational approach (such as continuum damage mechanics) has been developed and used, complementary to the experimental approach, to assist safe operation.
An, Lili, Lu, Zhongyu, Xu, Donglai, Xu, Qiang   +3 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Dynamic responses and damage mechanisms of low-rise reinforced concrete frame structures subjected to rockfall impacts

Journal of Asian Architecture and Building Engineering
Combined with the validations of the nonlinear material models, this study addresses the nonlinear dynamic response, damage mechanisms and failure modes of reinforced concrete frame structures under rockfall impacts, utilizing explicit dynamic analysis ...
Tao Tian, Wengao Lu, Haoran Wang
doaj   +1 more source