Results 51 to 60 of about 1,333,549 (315)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Mechanical damage evolution mechanism of coal injected with supercritical CO2 using Nanoindentation and XRD-EPMA technology

Meitan xuebao
CO2 geological storage technology is one of the effective technologies for achieving carbon reduction and the reuse of abandoned mine resources. In order to reveal the interaction mechanism between supercritical CO2 and coal during injection and its ...
Baisheng NIE, Dan ZHAO, Peng LIU, Lei WANG, Dalin WANG, Qingyi TU, Jingtao YANG, Xiyang ZHU   +7 more
doaj   +1 more source

Research on the Ablation Characteristics and Thermomechanical Coupling Matching of Continuous-Wave/Pulsed Combined Lasers

Photonics, 2022
In laser processing and electro-optical countermeasures, the laser ablation efficiency on the target is of great importance. Compared with traditional single laser irradiation, ablation by continuous-wave (CW)/pulsed combined laser has the advantages of ...
Jing Xiao, Guoying Feng, Gang Ren, Jinhua Han, Huijun Xia, You Wang, Wantao Deng, Tianyu Chen, Rongjun Guo   +8 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A continuous/discontinuous Galerkin formulation for a strain gradient-dependent damage model

, 2004
The numerical solution of strain gradient-dependent continuum problems has been hindered by continuity demands on the basis functions. The presence of terms in constitutive models that involve gradients of the strain field means that the $C^0$ continuity
G. N. Wells, MOLARI, LUISA, K. Garikipati   +2 more
core   +2 more sources

Crystal structure of the UvrB dimer: insights into the nature and functioning of the UvrAB damage engagement and UvrB-DNA complexes [PDF]

, 2012
UvrB has a central role in the highly conserved UvrABC pathway functioning not only as a damage recognition element but also as an essential component of the lesion tracking machinery.
Jukes, R., Barrett, T, Bagnéris, C, Bagneris, Claire, Zamfir, V.S., Barrett, Tracey E., Zamfir, VS, Webster, MP, Jukes, R, Webster, Matthew P., Kay, Christopher W.M., Kay, CW   +11 more
core   +1 more source

Mechanical response characteristics and damage mechanism of water-containing mudstone under low strain rate dynamic loading

Meitan xuebao
Accelerated instability and failure of surrounding water-rich mudstone in roadway under dynamic loading has become a prominent problem in deep coal resource mining, and it is of great significance to study the damage mechanism of water-containing ...
Guichen LI, Sen YANG, Yuantian SUN, Jinghua LI, Haoran HAO, Zeyu SHAO   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Study on the Microscopic Pore Characteristics and Mechanisms of Disturbance Damage in Zhanjiang Formation Structural Clay

Applied Sciences
To investigate the microscopic pore evolution characteristics of Zhanjiang Formation structural clay during the disturbance process, unconfined compressive strength tests, scanning electron microscopy (SEM), and X-ray diffraction (XRD) were conducted on ...
Yanhua Xie, Bin Tang, Shuaiyu Liu, Jicheng Xu, Binghui Zhang   +4 more
doaj   +1 more source

Area effect during the fracture process of high-Niobium-Titanium-Aluminum alloys under continuous tension loading-unloading

Frontiers in Materials, 2023
Based on the extracted results of the continuous tension loading-unloading testing, and observations of the corresponding cracks and fracture surfaces for the high-Niobium-Titanium-Aluminum alloys, both tensile damage and fracture mechanism were ...
Mingjie Zhong, Youzhi Lin, Youzhi Lin
doaj   +1 more source