Results 31 to 40 of about 30,599 (256)

New way for green and low-carbon development of coal industry under the target of “daul-carbon”

open access: yesMeitan xuebao
Under the background of “dual-carbon” goal and current technological conditions, coal, waste and carbon constitute an impossible triangle in the coal industry which severely constrains its green, low-carbon, and sustainable development.
Shuangming WANG   +10 more
doaj   +1 more source

Technical framework and engineering practice of whole process of underground water-preserved mining in western ecologically fragile mining areas

open access: yesMeitan xuebao
The scarce water resources and fragile ecological environment in western mining regions are insufficient to support high-intensity coal mining activities, readily triggering cascading ecological damage including groundwater depletion and vegetation ...
Jian SUN   +6 more
doaj   +1 more source

Tin, Ponds, Mangroves, and Tourism on Bangka Coast: The Dilemma of Money and Conservation [PDF]

open access: yesE3S Web of Conferences
The extensive expansion of tin mining in Bangka Island and a small part of the open sea is causing environmental damage in coastal areas. In recent years, the damage has been increased by the opening of shrimp ponds, leading to the reduction of mangrove ...
Ibrahim Ibrahim   +2 more
doaj   +1 more source

Calculation of Boundary Stripping Ratio Errors at the Stage of Quarries Designing [PDF]

open access: yesE3S Web of Conferences, 2019
The open pit mining method of solid minerals extracting is widely used both in Russia and in the whole world, and sets a general direction of mining industry development as its main tool, at least for the next decades.
Selyukov Alexei, Rybár Radim
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Effects of a simulated freezing construction environment on the mass concrete performance

open access: yes工程科学学报, 2022
Exhausted shallow resources have turned mining into deep mining, with the mining depth of most mines under construction being more than 1000 m. With the continuous increase of the mining depth of mineral resources, the thickness and strength grade of the
Rui-dong WU   +5 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Theory and technical system of coal ecological open-pit mining and its application

open access: yesMeitan xuebao
Large-scale open-pit coal mining will cause ecological problems such as land excavation and occupation, groundwater drainage, soil erosion, vegetation destruction, air pollution, and regional landscape damage. The selection of existing open-pit coal mine
Quansheng LI
doaj   +1 more source

Indigenous bacterial bioremediation: Chromiumreducing capabilities of native strains from Halmahera [PDF]

open access: yesBIO Web of Conferences
Indonesia, with its abundant natural resources, faces significant environmental degradation from open-pit mining, that lead to deforestation and heavy metal contamination, which pose dangers to humans and ecosystem.
Husaini Ahmad Fadhlullah   +4 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

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