Results 61 to 70 of about 600,627 (295)

Seismic damage in historic town centres and attenuation criteria

Annals of Geophysics, 1995
The structural significance of the damage scenarios characteristic of VIII and IX degrees on the MKS macroseismic scale is discussed with reference to the seismic behaviour of the buildings which make up the urban fabric of a historic town or city. In an
A. Giuffrè
doaj   +1 more source

Probabilistic soil moisture projections to assess Great Britain's future clay-related subsidence hazard [PDF]

, 2015
Clay-related subsidence is Great Britain’s (GB) most damaging soil-related geohazard, costing the economy up to £500 million per annum. Soil-related geohazard models based on mineralogy and potential soil moisture deficit (PSMD) derived from historic ...
Farewell, Timothy S., Hallett, Stephen H., Pritchard, Oliver G.   +2 more
core   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Damage Detection in Post-Tensioned Slab Using 2D Wavelet Transforms [PDF]

Journal of Rehabilitation in Civil Engineering, 2017
Earthquake force, loading more than structural capacity, cracking, material fatigue, and other unpredicted events are undeniable in the structure life cycle in order that environmental conditions of the structure would be changed and treats health ...
Seyed Rohollah Hoseini Vaez, Ehsan Dehghani, Vahid Babaei   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Atmospheric and geological CO2 damage costs in energy scenarios [PDF]

Environmental Science & Policy, 2006
Abstract Geological carbon dioxide capture and storage (CCS) is currently seriously considered for addressing, in the near term, the problem of climate change. CCS technology is available today and is expected to become an increasingly affordable CO2 abatement alternative.
Koen Smekens, Bob van der Zwaan
openaire   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Consequences of asteroid fragmentation during impact hazard mitigation [PDF]

, 2009
The consequences of the fragmentation of an Earth-threatening asteroid due to an attempted deflection are examined in this paper. The minimum required energy for a successful impulsive deflection of a threatening object is computed and compared to the ...
Davis D. R., G. Radice, Gault D. E., Goldstein H., Harris A. W., J. P. Sanchez, M. Vasile, Melosh H. J., Stokes G. H.   +8 more
core   +1 more source