Results 91 to 100 of about 3,378,493 (310)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The Punitive Damages Calculus: The Differential Incidence of State Punitive Damages Reforms

open access: yesSouthern Economic Journal, 2017
State punitive damages reforms have altered how courts award punitive damages. We model the decision to award punitive damages as a two-step process involving the decision to award any punitive damages and the decision of what amount to award. For the Civil Justice Survey of State Courts samples of trial court verdicts, punitive damages caps reduce the
Benjamin J. McMichael, W. Kip Viscusi
openaire   +3 more sources

The Pathology of the Role of Agents in the Realization of the Islamic State from the Perspective of Ayatollah Khamenei [PDF]

open access: yesدولت‌پژوهی
IntroductionAfter the victory of the Islamic Revolution in February 1978, the Islamic Republic was founded on two core principles: divine sovereignty and popular sovereignty.
Elaheh Sadeghi
doaj   +1 more source

A stress-based macroscopic approach for microcracks unilateral effect [PDF]

open access: yes, 2010
The question of the nonlinear response of brittle materials undergoing elastic damage is investigated here. Owing to the specific nature of microcracking, the macroscopic behaviour of these materials is complex, generally anisotropic owing to the ...
Cormery, Fabrice, Welemane, Hélène
core   +4 more sources

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The relationship between observed fatigue damage and life estimation models [PDF]

open access: yes
Observations of the surface of laboratory specimens subjected to axial and torsional fatigue loadings has resulted in the identification of three damage fatigue phenomena: crack nucleation, shear crack growth, and tensile crack growth.
Kurath, Peter, Socie, Darrell F.
core   +1 more source

Crashworthiness assessment considering the dynamic damage and failure of a dual phase automotive steel

open access: yes, 2020
Analyzing crash worthiness of the automotive parts has been posing a great challenge in the sheet metal and automotive industry since several decades.
Chandran, Sarath, Verleysen, Patricia
core  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Teoretical basis for the study of reparation by the state physical person, the victim of a criminal offence

open access: yesПроблеми Законності, 2016
Theoretical aspects of harm caused a criminal offence, that is, damage that is the basis for the adoption of measures to ensure reparation to the victim, in the science of civil procedural law received significant attention.
Наталія Анатоліївна Хмельова
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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