Results 201 to 210 of about 3,378,493 (310)

Proceedings of the 5th Annual United States Army Institute of Surgical Research Summer Undergraduate Research Internship Program 2017

Journal of Translational Medicine, 2017
Ryan Leone, Katie J. Jensen, Claire Abijay, Troy Dolmetsch, Natalie Koons, Daniel N. Darlington, Andrew P. Cap, Xiaowu Wu, Christopher P. Delavan, Maryanne C. Herzig, Barbara A. Christy, Kelley M. Kempski, August N. Blackburn, Robert A. De Lorenzo, Megan B. Blackburn, Matthew C. Donald, Harold G. Klemcke, Brenna K. Harrington, Celestine J. He, Belinda I. Gómez, Tony Chao, Joshua S. Little, Tiffany C. Heard, Michael A. Dubick, David M. Burmeister, Amy Xu, Kerfoot Walker III, Arezoo Mohammadipoor, Luis Rodriguez, Teryn Roberts, Andriy Batchinsky, Leopoldo Cancio, Ben Antebi, Ryan A. Walford, Colby S. McIntosh, Grantham C. Peltier, Umang Sharma, Robbie K. Montgomery, Michael A. Meledeo, James A. Bynum, Sarah Lovelace, Larry Estlack, Katherine Jensen, Lexi Kazen, Lee C. Mangum, Gerardo R. Garcia, Kevin S. Akers   +46 more
doaj   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Influence of confining pressure and stress amplitude on the mechanical properties and permeability characteristics of coal. [PDF]

Sci Rep
Yang H, Qin D, Liu H, Sun X, Ran Q, Hu Y.   +5 more
europepmc   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Correction: Photobiomodulation modulates mitochondrial energy metabolism and ameliorates neurological damage in an APP/PS1 mouse model of Alzheimer's disease. [PDF]

Alzheimers Res Ther
Chen H, Li N, Liu N, Zhu H, Ma C, Ye Y, Shi X, Luo G, Dong X, Tan T, Wei X, Yin H.   +11 more
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Probabilistic modeling of cell cycle dynamics in response to cell cycle targeting chemotherapy drugs to guide treatment strategies. [PDF]

PLoS Comput Biol
Ma C, Gurkan-Cavusoglu E.
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Experimental Study on Acoustic Emission Signals Under Different Processing States of Laser-Assisted Machining of SiC Ceramics. [PDF]

Micromachines (Basel)
Cao C, Zhao Y, Hu X, Cui X.
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source