Results 81 to 90 of about 12,996,719 (308)

The State-of-the-Art on Framework of Vibration-Based Structural Damage Identification for Decision Making

, 2017
Research on detecting structural damage at the earliest possible stage has been an interesting topic for decades. Among them, the vibration-based damage detection method as a global technique is especially pervasive.
X. Kong, C. Cai, Jiexuan Hu
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Study on Suppression of Vortex-Induced Vibrations of a Rotating Cylinder with Dual Splitter Plates

Journal of Marine Science and Engineering
To investigate the suppression method for vortex-induced vibrations (VIV) of two-degree-of-freedom (2-DOF) rotating cylinders with dual splitter plates, numerical simulations are conducted at a Reynolds number of 200, a mass ratio of 2.6, and rotation ...
Jiaqi Li, Qiongfang Qi, Zonghao Sun, Yongkang Yang, Yaowen Han, Wei Chen, Jiangyan Shao, Binrong Wen, Xiaobin Li   +8 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The Punitive Damages Calculus: The Differential Incidence of State Punitive Damages Reforms

Southern Economic Journal, 2017
State punitive damages reforms have altered how courts award punitive damages. We model the decision to award punitive damages as a two-step process involving the decision to award any punitive damages and the decision of what amount to award. For the Civil Justice Survey of State Courts samples of trial court verdicts, punitive damages caps reduce the
Benjamin J. McMichael, W. Kip Viscusi
openaire   +3 more sources

Genome sequence resources for three strains of the genus Clonostachys

BMC Genomic Data
Objective Clonostachys, a genus with rich morphological and ecological diversity in Bionectriaceae, has a wide distribution among diverse habitats. Several studies have reported Clonostachys fungi as effective biological agents against multiple fungal ...
Zongping Sun, Fan Zhang, Nana Zhong, Kang Zhou, Jun Tang   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The Pathology of the Role of Agents in the Realization of the Islamic State from the Perspective of Ayatollah Khamenei [PDF]

دولت‌پژوهی
IntroductionAfter the victory of the Islamic Revolution in February 1978, the Islamic Republic was founded on two core principles: divine sovereignty and popular sovereignty.
Elaheh Sadeghi
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source