Results 81 to 90 of about 3,378,493 (310)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Stress state dependent damage modeling of self-pierce riveting process simulation using GISSMO damage model

open access: yesJournal of Advanced Joining Processes, 2020
In this study, the damage model GISSMO (Generalized Incremental Stress State dependent damage MOdel) is used to describe the evolution of ductile damage and predict the onset of fracture during the self-pierce riveting of thin aluminum (EN AW-5182 ...
M. Otroshi, M. Rossel, G. Meschut
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Some problems and errors in cytogenetic biodosimetry [PDF]

open access: yes, 2016
Human radiosensitivity is a quantitative trait that is generally subject to binomial distribution. Individual radiosensitivity, however, may deviate significantly from the mean (by 2-3 standard deviations).
Kilchevsky, Alexander   +3 more
core   +5 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Study on Suppression of Vortex-Induced Vibrations of a Rotating Cylinder with Dual Splitter Plates

open access: yesJournal of Marine Science and Engineering
To investigate the suppression method for vortex-induced vibrations (VIV) of two-degree-of-freedom (2-DOF) rotating cylinders with dual splitter plates, numerical simulations are conducted at a Reynolds number of 200, a mass ratio of 2.6, and rotation ...
Jiaqi Li   +8 more
doaj   +1 more source

Modeling anisotropic damage in elasto-plastic materials with structural defects [PDF]

open access: yes, 2013
The paper deals with models for elasto-plastic materials with continuously distributed micro defects (micro cracks, micro voids, extra-matte), compatible with the principle of imbalance of the free energy.
Cleja-Tigoui, Sanda, Tigoui, Victor
core  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Genome sequence resources for three strains of the genus Clonostachys

open access: yesBMC Genomic Data
Objective Clonostachys, a genus with rich morphological and ecological diversity in Bionectriaceae, has a wide distribution among diverse habitats. Several studies have reported Clonostachys fungi as effective biological agents against multiple fungal ...
Zongping Sun   +4 more
doaj   +1 more source

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