Results 151 to 160 of about 228,197 (315)

Turkey Damage Survey: A Wildlife Success Story Becoming Another Wildlife Damage Problem

, 2000
Wild turkey (Meleagris gallopavo) populations have been restored and enhanced through introductions and reintroductions in 49 of the 50 states to huntable populations within the last 30 years. Populations are presently estimated to exceed 4 million birds within the United States.
Miller, James E., Tefft, Brian C., Eriksen, Robert E., Gregonis, Mike   +3 more
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Comment on: Variations in morphology and patency of disposable hydrodissection cannulas used in cataract surgery. [PDF]

J Cataract Refract Surg
Alwitry A.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A large exploratory survey of electroconvulsive therapy recipients, family members and friends: what information do they recall being given? [PDF]

J Med Ethics
Read J, Harrop C, Morrison L, Hancock SP, Johnstone L, Cunliffe S.   +5 more
europepmc   +1 more source

Archaeological Damage from Offshore Dredging: Recommendations for Pre-Operational Surveys and Mitigation During Dredging to Avoid Adverse Impacts: Technical Summary

, 2004
Jacqueline Michel, Gordon P. Watts, Rob Bairn, Tim Kenny   +3 more
openalex   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

What Makes Household Sanitation Systems Resilient to Floods? Evidence from Ethiopia, Uganda, and Nepal. [PDF]

ACS ES T Water
Kohlitz J, Geremew A, Okurut K, Poudel P, Ghimire A, Nijhawan A, Valenzuela A, Falletta J, Manandhar-Sherpa A, Willetts J, Howard G.   +10 more
europepmc   +1 more source

A Survey Low Temperature Damage of Tea Tree at South Korea in 2011 [PDF]

, 2012
Jung–Gyu Hwang, Yong‐Duck Kim
openalex   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source