Results 241 to 250 of about 228,197 (315)

Nurses' Perceptions and Utilization Plans for Applying Companion Robots to Acute Stroke Patient Care: A Delphi Study. [PDF]

Healthc Inform Res
Choo HJ, Lee SM.
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Discordance Between Patients and Physicians on Key Determinants of Systemic Lupus Erythematosus Burden: Insights From a French Comprehensive Survey. [PDF]

ACR Open Rheumatol
Chiche L, Devilliers H, Vallée R, Taccola C, Ghezaiel-Etienne M, Tripoli N, Rivière M, Scherlinger M.   +7 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Evaluating the potential of sNfL as a biomarker in MS management in the UK: insights from SUNLIT survey. [PDF]

BMC Neurol
Gnanapavan S, Arun T, Gallagher P, Rushworth M, Marsh J, Kondori NR.   +5 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Knowledge and acceptability of the Lémann Index as a tool to measure disease progression and bowel damage in Crohn's disease: results from an international survey. [PDF]

Intest Res
Wong C, Burisch J, Ungaro RC, Buisson A, Lambert J, Colombel JF, Torres J, Arebi N.   +7 more
europepmc   +1 more source

LITERATURE SURVEY ON DAMAGE DUE TO THE 1933 NOTO PENINSULA EARTHQUAKE

Toshihiko MIZUTA, Hiroshi KAGAMI
openalex   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

AERIAL SURVEY OF DAMAGES DUE TO EARTHQUAKE

Journal of the Japan society of photogrammetry, 1965
openaire   +2 more sources