Results 101 to 110 of about 271,153 (306)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

29 October 2007, Çameli earthquake and structural damages at unreinforced masonry buildings [PDF]

open access: yesNatural Hazards and Earth System Sciences, 2008
A recent earthquake of M=4.9 occurred on 29 October 2007 in Çameli, Denizli, which is located in a seismically active region at southwest Anatolia, Turkey.
H. Kaplan   +9 more
doaj  

Sustainable Consolidation of Churches that are historic monuments damaged by earthquakes [PDF]

open access: yesMATEC Web of Conferences
Historical buildings were built using local materials and technologies and suffered degradation of their structural elements over time due to abandonment, material degradation, unauthorised interventions or the action of extreme events such as ...
Mosoarca Marius   +3 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Building Damage from Expansive Steel Slag Backfill

open access: yesJournal of the Soil Mechanics and Foundations Division, 1969
Expanding steel slage backfill was unexpectedly found to be the cause of vertical movements of the floor of a basementless building that resulted in significant damage to window and door frames. Five years after construction some parts of the building were still heaving at a rate of 1 cm per yr. Swelling properties of the slag when exposed to different
Crawford, C. B., Burn, K. N.
openaire   +3 more sources

The application of cogeneration systems to the cooling of food and buildings in East Timor : a thesis presented in partial fulfilment of the requirements for the degree of Master of Technology at Massey University [PDF]

open access: yes, 2001
Cogeneration is generation of both heat and power simultaneously using a single primary energy input. Cogeneration recovers "waste heat "from a conventional power generation plant to produce useful energy, leading to the increased overall efficiency of ...
Saldanha, Estanislau de Sousa
core  

Detecting damaged buildings using real-time crowdsourced images and transfer learning. [PDF]

open access: yesSci Rep, 2022
Chachra G   +6 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Beirut Heritage Initiative: Safeguarding the City’s Built Heritage After the August 4, 2020, Port Explosion

open access: yesJournal of Traditional Building, Architecture and Urbanism, 2021
The devastating explosion in Beirut’s port on August 4, 2020 will forever be engraved in the memory of the Lebanese people. Within moments, a city with over 5,000 years of history was in ruins.
Yasmine Elmajzoub
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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