Results 141 to 150 of about 1,303,184 (394)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

LA EJECUCIÓN DE ACTOS DAÑOSOS COMO FUNDAMENTO DE EXTINCIÓN DEL CONTRATO DE TRABAJO

open access: yesRevista de Derecho (Coquimbo)
El Código del Trabajo chileno establece como causa de extinción del contrato la realización por parte del trabajador de actos que provoquen perjuicio al empleador. Tradicionalmente, esta causa de despido se ha vinculado con los actos de sabotaje.
PEDRO IRURETA URIARTE
doaj   +1 more source

Numerical analysis of reinforced concrete shear keys in immersion joints

open access: yes, 2017
Immersion joints are susceptible to be damaged first under various loadings due ito their smaller stiffhess compared to the adjacent tunnel elements. The induced Ideformations and the forces in the joint are transferred by shear keys.
Taerwe, Luc, Xiao, Wenhao, Yuan, Yong
core  

Of Punitive Damages, Tax Deductions, and Tax-Aware Juries: A Response to Polsky and Markel [PDF]

open access: yes, 2010
In “Taxing Punitive Damages,” Gregg D. Polsky and Dan Markel argue that defendants paying punitive damages are under-punished relative to juries’ intentions, because tax-unaware juries do not take into account the fact that the deductibility of punitive ...
Zelenak, Lawrence A.
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Natural Disasters, Relief Aid, and Household Vulnerability in Pakistan: Evidence from a Pilot Survey in Khyber Pakhtunkhwa [PDF]

open access: yes
Based on a pilot survey, we analyze the damages caused by floods in Pakistan, 2010, the istribution of aid, and the extent of recovery at he household level.
Khan, Humayun   +3 more
core  

Nonlinear temperature effects indicate severe damages to U.S. crop yields under climate change

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2009
W. Schlenker, M. Roberts
semanticscholar   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Gone with the Wind: JP and the Right to Clean Air Under EU Law

open access: yesEuropean Papers
(Series Information) European Papers - A Journal on Law and Integration, 2024 9(1), 337-366 | Article | (Table of Contents) I. Introduction. - II. Air quality and EU law. - III. The CJEU’s case law on AQD. - iii.1. Public enforcement. - iii.2.
Luca Calzolari
doaj   +1 more source

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