Results 161 to 170 of about 1,303,184 (394)
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
An Exploration of “Non-Economic” Damages in Civil Jury Awards [PDF]
, 2014 Using three primary data sources plus three supplemental sources discussed in an appendix, this paper examines how well non-economic damages could be predicted by economic damages and at how the ratio of non-economic damages to economic damages changed ...
Kritzer, Herbert M. +2 more
core +3 more sources
Pengaruh Multiple Damages Struktur Kapal Berbahan Sandwich Panel Menggunakan Respon Getaran
, 2021 Windra Iswidodo +2 more
openalex +1 more source
Acute Complications of COVID-19 With Lasting Damages: A Case of Severe Long-Term Sequelae in a Middle-Aged Female Post COVID-19 [PDF]
, 2022 Mir Sulayman Khan +6 more
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
On the consideration of potential harm in the award of punitive damages [PDF]
Multiple empirical studies find that juries/courts take account of potential harm in the determination of punitive damages. The received view in economic theory, however, is that punitive damages should not depend on potential harm.
Bharat Bhole, Jeffrey Wagner
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Disgorgement and 'licence fee damages' in contract [PDF]
, 2004 This article offers a theoretical basis for the limited availability of claims in respect of the benefit of a breach of contract in the light of recent cases.
Jaffey, P
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Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Punitive Damages and the Processing of Tort Claims [PDF]
Punitive damages are one of the most controversial aspects of tort litigation and have been the subject of various theoretical, empirical, and experimental studies. One criticism of punitive damages refers to the effect that they have on civil litigation
David B. Mustard +2 more
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