Results 241 to 250 of about 1,303,184 (394)

A high resolution multipollutant assessment of health damages due to the onroad sector in Boston, Massachusetts

Manish Soni, Saravanan Arunachalam, M. V. S. Ramarao, C. Efstathiou, Christopher Rick, Laura Buckley, C. M. Dinesh, Mary D. Willis, Frederica Perera, Patrick L. Kinney, Jonathan I. Levy, Jonathan J. Buonocore   +11 more
openalex   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

A scalable data driven geospatial framework for climate risk assessment. [PDF]

Sci Rep
Abdel-Mooty MN, Coulibaly P, El-Dakhakhni W.   +2 more
europepmc   +1 more source

Photoinduced processes, radiation interaction with material and damages - material hardness

, 2015
Milesa Srećković, Stanko Ostojić, Jelena Ilić, Zoran Fidanovski, Sanja Jevtić, Dragan Knežević, Marija Obrenović   +6 more
openalex   +2 more sources

Climate damages and adaptation potential across diverse sectors of the United States

Nature Climate Change, 2019
J. Martinich, A. Crimmins
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Investigation of deep learning approaches for automated damage diagnostics in fiber metal laminates using Detectron2 and SAM. [PDF]

Front Artif Intell
Kumar S, Bosse S, Shah C.
europepmc   +1 more source

Register of Damages Caused by the Aggression of the Russian Federation in Ukraine: the Creation and Main Objectives of the Mechanism

Anna Dąbrowska
openalex   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Beyond the limit: The estimated air pollution damages of overshooting the temperature target. [PDF]

Sci Adv
Rodés-Bachs C, Drouet L, Rafaj P, Tavoni M, Reis LA.   +4 more
europepmc   +1 more source