Results 231 to 240 of about 4,496,925 (290)

Collagen‐Binding IL‐15 Immunocytokine Armed Oncolytic Adenovirus Establishes a Self‐Reinforcing Immunostimulatory Milieu to Potentiate Antitumor Immunity

Advanced Science, EarlyView.
Repurposing the dense tumor stroma from a physical barrier into an anchoring scaffold, an engineered oncolytic adenovirus encoding IL15C‐CBD overcomes the immunosuppressive microenvironment in triple‐negative breast cancer. Intratumoral viral replication secretes this collagen‐anchored immunocytokine, forming a localized cytokine depot.
Yaqi Yang, Xiaoxiao Liu, Junqiang Ding, Jinliang Xu, Jianhua Zhang, Hanchang Zhang, Rong Yang, Sha Li, Lu Zheng, Runping Su, Yue Zhao, Jianxiao Wu, Hao Li, Changyou Zhan, Xihui Gao   +14 more
wiley   +1 more source

Output-Only Modal Identification of Civil Engineering Structures Based on Parametric Complexity Pursuit. [PDF]

Sensors (Basel)
Li J, Gao J, Zhang S, Mircevska V, Cao M.   +4 more
europepmc   +1 more source

Spatiotemporally Controlled Sequential Chemo‐Immunotherapy Activates Pyroptosis for Robust Anti‐Tumor Immunotherapy

Advanced Science, EarlyView.
A glutathione and ultrasound dual‐responsive cerasome achieves sequential co‐delivery of gemcitabine and BMS1166 in tumors. Chemotherapy priming followed by on‐demand PD‐L1 blockade synergistically amplifies anti‐tumor immunity, inhibiting primary tumor growth, distant metastasis and inducing durable immune memory.
Suhui Sun, Ruiqi Wu, Qingshuang Tang, Yunli Xu, Wanrui Shi, Mengxin Wang, Haonan Wang, Yan Luo, Cheng Ma, Xiaolong Liang   +9 more
wiley   +1 more source

Preserved and reduced ejection fraction manifest as two unique phenotypes of diastolic dysfunction-a mechanistic study. [PDF]

Eur Heart J Imaging Methods Pract
McColl H, Brookes M, Price M, Fulthorp E, McGrady M, Lal S, Ugander M.   +6 more
europepmc   +1 more source

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

Advanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng, Yingfei Zhang, Chong Wu, Qijia Duan, Mengqi Fan, Kuan Wang, Shirong Cai, Immihan Ceren Yasa   +7 more
wiley   +1 more source

Energy-Aware Finite-Horizon MPC Coordination of Adaptive VSG Inertia and BESS Control for Transient-Stability Enhancement in Renewable-Dominated Low-Inertia Hybrid Microgrids. [PDF]

Sensors (Basel)
Rodríguez Romero JD, Hernández-Mayoral E, Gamboa SA, Torres-García V, Madrigal-Martínez M, Trujillo-Caballero JC, Jaramillo OA.   +6 more
europepmc   +1 more source

Bioinspired Metastable Transient Peeling for Repeatable Rapid Release

Advanced Science, EarlyView.
Inspired by the explosive seed ejection of the squirting cucumber, this work introduces metastable transient peeling that temporally regulates stored interfacial energy release via a tunable energy barrier. A viscoelastic hemispherical gripper achieves 52 ms ultrafast, residue‐free release with 300 000‐cycle durability, enabling damage‐free handling of
Lvzhou Li, Qingyue Li, Yao Hu, Xu Dong, Xiangli Wen, Kai Zhu, Yaoyao Jiang, Yu Tian, Jianning Ding   +8 more
wiley   +1 more source

Glial syncytial control fields and the low-frequency resonome of the human brain. [PDF]

Front Hum Neurosci
Ballús Santacana A.
europepmc   +1 more source

Spatial Au+ Mapping Reveals a Self‐Amplifying Anti‐Tumor Immunity Loop Driven by Au(I) Complexes

Advanced Science, EarlyView.
The first report of spatial Au+ mapping of a representative gold complex (Au9). Macrophages, DCs, and tumor cells ranked as the top three in Au+ enrichment after Au9 treatment. Interestingly, Au9 treatment could induce ferroptosis and suppress cellular cholesterol, further eliciting a self‐amplifying anti‐tumor immunity loop.
Zhongren Xu, Zhiyue Fan, Lin Lv, Wei Lu, Zhenfan Wen, Wukun Liu   +5 more
wiley   +1 more source

Perceptually AMQE-QLDPC coding for quantum image transmission over amplitude-damping channels. [PDF]

Sci Rep
Al-Hinai M, Asif HM, Kausar F.
europepmc   +1 more source