Results 71 to 80 of about 284,969 (269)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Exposure of the settlements in the Republic of Dagestan to landslide processes
Наука. Инновации. ТехнологииThe object of the study is the landslide activity in the Republic of Dagestan. The paper considers the results of systematization and analysis of various sources containing information on the activity and danger of landslide processes in the settlements ...
V. V. Razumov +4 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Oryx, 1975 The Italian grey partridge Perdix p. italica is in danger of extinction. It has been overhunted and stocks have been polluted by the importing and release of other subspecies. The author urges that the few small flocks of the pure native bird known to survive should be located and given strict protection.
openaire +3 more sources
Highways оf the chechen republic under the influence of rockslides аnd screes processes
Наука. Инновации. ТехнологииThe results of systematization and analysis of various sources containing information on the activity and danger of rockslides-screes processes on the roads of the Chechen Republic in 2008-2022 are considered.
V. V. Razumov +4 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Cracow Indological Studies, 2019 Icons, Troubled and Troubling. Some Observations from the Vimānārcanakalpa The Vimānārcanakalpa, a text of around the 10th century C.E., belongs to the Vaikhānasa medieval corpus of ritual manuals.
Gérard Colas
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Proceedings of the National Academy of Sciences, 2016 CRISPR-Cas loci encode for an adaptive immune system in prokaryotes that provides defense against viruses (1) and plasmids (2) that infect these organisms. CRISPR loci contain a series of repetitive sequences intercalated with short sequences derived from invading viruses and plasmids (3⇓–5). These short sequences, called spacers, are acquired from the
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source