Results 271 to 280 of about 879,070 (310)

Role of real-world evidence from patient registries for psoriasis in decision-making: a systematic review. [PDF]

BMJ Open Qual
Passero L, Simon TA, Zhong Y, Zhuo J, Varga S, Armstrong AW.   +5 more
europepmc   +1 more source

The Global Airways in Practice: Long‐term Effects of Mepolizumab With or Without FESS on Type 2 Inflammation in Patients With CRSwNP

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammatory disease often associated with asthma. The global airway hypothesis suggests bidirectional inflammatory interactions between upper and lower airways. Mepolizumab, an anti–IL‐5 therapy, treats conditions systemically, while functional endoscopic sinus surgery ...
Jens Tidemandsen, Vibeke Backer, Anne Sophie Homøe, Thomas H. L. Jensen, Kasper Aanæs, Howraman Meteran, Morten Hostrup, Lukas Moesgaard, Christiane Haase, Peter G. Gibson   +9 more
wiley   +1 more source

Refined Algorithm for Identifying Recurrence Among Patients with Non-Metastatic Colorectal Cancer Based on Danish National Health Data Registries. [PDF]

Clin Epidemiol
Gögenur M, Bräuner KB, Löffler L, Olsen ASF, Gundestrup AK, Jakobsen PCH, Kleif J, Bertelsen CA, Gögenur I.   +8 more
europepmc   +1 more source

Local Specific IgE Levels Can Predict and Monitor the Therapeutic Response to Subcutaneous Immunotherapy With House Dust Mite

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Identifying predictive and monitoring biomarkers for allergen immunotherapy response is crucial for enhancing clinical efficacy. This study aims to investigate the systemic and local levels of immunoglobulins and identify potential biomarkers in house dust mite (HDM) allergic rhinitis (AR) patients who are undergoing subcutaneous ...
Xu Xu, Jingyun Li, Xu Zhang, Yu Song, Lin Xi, Luo Zhang, Yuan Zhang   +6 more
wiley   +1 more source

The association of body mass index with patient outcomes after shoulder replacement surgery: Population-based cohort study using linked national data from the United Kingdom and Denmark. [PDF]

PLoS Med
Valsamis EM, Larsen JB, Sayers A, Jones T, Gwilym SE, Kjær-Kristensen P, Thillemann TM, Mechlenburg I, Whitehouse MR, Rees JL.   +9 more
europepmc   +1 more source

Adropin modulates pancreatic cell proliferation and glutathione levels in an animal model of type 1 diabetes mellitus

Animal Models and Experimental Medicine, EarlyView.
Adropin is related to the energy homeostasis‐associated gene. It significantly increased glutathione reductase enzyme levels in the pancreas of experimental diabetic rats. Adropin may reduce the severity of diabetes and its complications. Cell proliferation in the exocrine is reduced after the administration of adropin.
Ifrah I. Ali, Crystal D'Souza, Abderrahim Nemmar, Shreesh Ojha, Ernest A. Adeghate   +4 more
wiley   +1 more source

Relative Effectiveness of High-Dose Versus Standard-Dose Influenza Vaccination Against Hospitalizations and Deaths According to Frailty Score: A Post Hoc Analysis of the DANFLU-1 Randomized Trial. [PDF]

J Infect Dis
Espersen C, Johansen ND, Modin D, Janstrup KH, Nealon J, Samson S, Loiacono MM, Harris RC, Andrew MK, Larsen CS, Jensen AMR, Landler NE, Claggett BL, Solomon SD, Landray MJ, Gislason GH, Køber L, Jensen JUS, Sivapalan P, Biering-Sørensen T.   +19 more
europepmc   +1 more source

Temporal glomerular gene expression dynamics during disease progression in a mouse model of hypertension‐accelerated diabetic kidney disease

Animal Models and Experimental Medicine, EarlyView.
The current study characterized temporal changes in glomerular gene expression, pathology, and biomarkers in a mouse model of hypertension‐accelerated diabetic kidney disease (DKD). Progressive albuminuria and glomerulosclerosis were paralleled by dynamic transcriptomic changes associated withmetabolic dysfunction, extracellular matrix remodeling, and ...
Adam B. Marstrand‐Jørgensen, Frederikke Emilie Sembach, Maria Ougaard, Ditte Hansen, Mette Viberg Østergaard, Henrik H. Hansen, Louise S. Dalbøge, Ole Jørgen Kaasbøll, Michael Christensen   +8 more
wiley   +1 more source

Drowning incidents treated by the Danish Royal Air Force's Search and Rescue helicopters: a 10-year nationwide registry-based cohort study. [PDF]

Scand J Trauma Resusc Emerg Med
Breindahl N, Sunekaer K, Bitzer K, Wolthers SA, Laugesen M, Lynnerup AS, Steinmetz J, Christensen HC.   +7 more
europepmc   +1 more source

A Growth Chart for KBG Syndrome

American Journal of Medical Genetics Part A, EarlyView.
Karen J. Low, Elena Martinez‐Cayuelas, Berta Almoguera, Purin Marin‐Reina, Allan Bayat, Charlotte W. Ockeloen, Tim J. Cole   +6 more
wiley   +1 more source