Results 81 to 90 of about 48,675 (245)

Strengths and weaknesses of 'real-world' studies involving non-vitamin K antagonist oral anticoagulants. [PDF]

, 2018
Randomised controlled trials (RCTs) provide the reference standard for comparing the efficacy of one therapy or intervention with another. However, RCTs have restrictive inclusion and exclusion criteria; thus, they are not fully representative of an ...
Camm, AJ, Fox, KAA
core   +1 more source

Validation of a Genetic Risk Score Combined With Clinical Variables for Predicting Pulmonary Fibrosis in Early Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). This study aimed to externally validate a genetic risk score (GRS) and a combined risk score (CRS) for predicting the risk of RA‐associated PF in an independent cohort of patients with early RA.
Mikael Brink, Austin Wheeler, Bryant R. England, Solbritt Rantapää‐Dahlqvist   +3 more
wiley   +1 more source

Initiation and persistence with dual antiplatelet therapy after acute myocardial infarction:a Danish nationwide population-based cohort study [PDF]

, 2016
OBJECTIVES: The study investigated dual antiplatelet therapy (DAPT) patterns over time and patient characteristics associated with the various treatments in a myocardial infarction (MI) population.
Broe, Anne, Diness, Thomas Goldin, Emneus, Martha, Gislason, Gunnar H, Green, Anders, Hasvold, Pål, Pottegård, Anton   +6 more
core   +2 more sources

Optoelectrical Devices for Neural Interfacing: Engineering Integration, Stability, and Multimodal Sensing

Advanced Healthcare Materials, EarlyView.
Implantable optoelectrical devices are an effective resource for the modulation and monitoring of neural activity with high spatiotemporal resolution. This review discusses current challenges faced by these devices and outlines future perspectives for the development of next‐generation neural interfaces targeting chronic, multisite, and multimodal ...
Stella Aslanoglou, Barbara Spagnolo, Antonio Balena, Massimo De Vittorio, Ferruccio Pisanello   +4 more
wiley   +1 more source

Long-Term Opioid Therapy in Spine Center Outpatients: Protocol for the Spinal Pain Opioid Cohort (SPOC) Study

JMIR Research Protocols, 2020
BackgroundSpinal pain is the leading cause of patient-years lived with chronic pain and disability worldwide. Although opioids are well documented as an effective short-term pain-relieving medication, more than a few weeks of treatment may result in a ...
Manniche, Claus, Stokholm, Lonny, Ravn, Sophie L, Andersen, Tonny E, Brandt, Lars PA, Rubin, Katrine H, Schiøttz-Christensen, Berit, Andersen, Lars L, Skousgaard, Søren G   +8 more
doaj   +1 more source

Longitudinal analysis of health care costs in patients with childhood onset inherited retinal dystrophies compared to healthy controls

BMC Ophthalmology, 2022
Background We evaluated health care costs in patients with childhood onset visual impairment caused by inherited retinal dystrophies (IRD). Methods The IRD cohort, identified from the Danish Registry of Blind and Partially Sighted Children, was compared ...
Line Kessel, Jakob Kjellberg, Rikke Ibsen, Annette Rasmussen, Kamilla Rothe Nissen, Morten la Cour   +5 more
doaj   +1 more source

A Comparison of Three Methods to Measure Asthma in Epidemiologic Studies: Results from the Danish National Birth Cohort [PDF]

, 2012
Asthma is a heterogeneous outcome and how the condition should be measured to best capture clinically relevant disease in epidemiologic studies remains unclear. We compared three methods of measuring asthma in the Danish National Birth Cohort (n>50.000).
Granström, Charlotta, Hansen, Susanne, Maslova, Ekaterina, Mortensen, Erik Lykke, Olsen, Sjurdur F., Strøm, Marin   +5 more
core   +3 more sources

Outcomes Associated With Oral Anticoagulants Plus Antiplatelets in Patients With Newly Diagnosed Atrial Fibrillation. [PDF]

, 2020
Importance: Patients with nonvalvular atrial fibrillation at risk of stroke should receive oral anticoagulants (OAC). However, approximately 1 in 8 patients in the Global Anticoagulant Registry in the Field (GARFIELD-AF) registry are treated with ...
Bassand, J-P, Camm, AJ, Dabrowski, E, Fitzmaurice, DA, Fox, KAA, GARFIELD-AF Investigators, Gersh, BJ, Gibbs, L, Goldhaber, SZ, Goto, S, Haas, S, Kakkar, AK, Luo, K, Misselwitz, F, Pieper, KS, Turpie, AGG, Velentgas, P, Verheugt, FWA   +17 more
core   +2 more sources

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

High inter-laboratory variability in the assessment of HER2-low breast cancer: a national registry study on 50,714 Danish patients [PDF]

, 2023
K. Nielsen, Michael Sode, Maj‐Britt Jensen, Tobias Berg, Ann Knoop, Bent Ejlertsen, Anne‐Vibeke Lænkholm   +6 more
openalex   +1 more source