Results 151 to 160 of about 218 (163)

Conformational restriction design of thiophene-biphenyl-DAPY HIV-1 non-nucleoside reverse transcriptase inhibitors

, 2019
Ya-Li Sang, Sheng Han, Christophe Pannecouque, Erik De Clercq, Chunlin Zhuang, Fen‐Er Chen   +5 more
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Structure-based discovery of novel piperidine-biphenyl-DAPY derivatives as non-nucleoside reverse transcriptase inhibitors featuring improved potency, safety, and selectivity: From piperazine-biphenyl-DAPYs to piperidine-biphenyl-DAPYs

Wenjuan Huang, Christophe Pannecouque, Erik De Clercq, Shuai Wang, Fen‐Er Chen   +4 more
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Fragment Addition-Based Design of Heteroaromatic-Biphenyl-DAPYs as Potent and Orally Available Non-nucleoside Reverse Transcriptase Inhibitors Featuring Significantly Enhanced Safety

Wenjuan Huang, Christophe Pannecouque, Erik De Clercq, Shuai Wang, Fen‐Er Chen   +4 more
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Chiral resolution, absolute configuration assignment and biological activity of racemic diarylpyrimidine CH(OH)-DAPY as potent nonnucleoside HIV-1 reverse transcriptase inhibitors

, 2012
Shuang‐Xi Gu, Zhiming Li, Xiaodong Ma, Shiqiong Yang, Qiuqin He, Fen‐Er Chen, Erik De Clercq, Jan Balzarini, Christophe Pannecouque   +8 more
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Evidence for lack of specificity of the DA/DAPI technique

Cytogenetic and Genome Research, 1987
Abrisqueta Ja, Ana Perez-Castillo, M. A. Martín-Lucas   +2 more
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Discovery of novel DAPY-IAS hybrid derivatives as potential HIV-1 inhibitors using molecular hybridization based on crystallographic overlays

, 2017
Boshi Huang, Xueshun Wang, Xinhao Liu, Zihui Chen, Wanzhuo Li, Songkai Sun, Huiqing Liu, Dirk Daelemans, Erik De Clercq, Christophe Pannecouque, Peng Zhan, Xinyong Liu   +11 more
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Cell staining with DAPI: or a bit of both?

Trends in Genetics, 1989
openaire   +2 more sources

Novel fluorine-containing DAPY derivatives as potent HIV-1 NNRTIs: a patent evaluation of WO2014072419

, 2015
Qing Meng, Na Liu, Boshi Huang, Peng Zhan, Xinyong Liu   +4 more
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Structural optimization of pyridine-type DAPY derivatives to exploit the tolerant regions of the NNRTI binding pocket

, 2016
Wen‐Ming Chen, Peng Zhan, Dirk Daelemans, Jiapei Yang, Boshi Huang, Erik De Clercq, Christophe Pannecouque, Xinyong Liu   +7 more
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[Discovery and development of diarylpyrimidines (DAPYs) as next-generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs)].

, 2010
Xingtao Tian, Lan Xie
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