Results 81 to 90 of about 38,964 (188)

Real‐world effectiveness and safety of acalabrutinib in chronic lymphocytic leukaemia: Multicentre experience

British Journal of Haematology, EarlyView.
Summary Chronic lymphocytic leukaemia (CLL) primarily affects elderly patients with comorbidities, yet real‐world data on acalabrutinib, a second‐generation Bruton's Tyrosine Kinase (BTK) inhibitor, remain limited outside clinical trials, particularly in Italy.
Andrea Duminuco, Dario Leotta, Alessandro Allegra, Daniele Caracciolo, Laura Caruso, Annalisa Chiarenza, Vittorio Del Fabro, Valentina Di Martina, Amalia Figuera, Paolo Fabio Fiumara, Massimo Gentile, Vanessa Innao, Salvatrice Mancuso, Enrica Antonia Martino, Antonio Mosca, Giovanna Motta, Francesca Pedalino, Marco Rossi, Fabio Stagno, Giorgio Tona, Francesco Di Raimondo, Giuseppe Alberto Palumbo   +21 more
wiley   +1 more source

Evidence That the Protein Phosphatase Activity of PTEN Contributes to Embryonic Development and Tumor Suppression

Cancer Science, EarlyView.
Mice expressing only mutant PTEN Y138L, a protein which shows normal suppression of cellular AKT yet lacks protein phosphatase activity, die in utero, and heterozygous mice display a range of tumors. This indicates both the lipid and protein phosphatase activities of PTEN work together for normal tumor suppression and embryonic development.
Priyanka Tibarewal, Laura Spinelli, Nisha Kriplani, Helen Wise, Nadege Poncet, Giulia Marzano, Karen E. Anderson, Katarzyna M. Grzes, Zofia Varyova, Mahreen Adil, C. Peter Downes, Phillip T. Hawkins, Len R. Stephens, Kate G. Storey, Doreen A. Cantrell, Bart Vanhaesebroeck, Nicholas R. Leslie   +16 more
wiley   +1 more source

De roca y flor de lis: Rubén Darío y Manuel Machado De roca y flor de lis: Rubén Darío and Manuel Machado

Cuadernos del CILHA, 2009
El presente artículo estudia la relación amistosa y literaria establecida entre Rubén Darío y Manuel Machado y analiza la presencia de la obra dariana en Alma y Caprichos de Manuel Machado.The present paper studies the friendship and literary relations ...
Rafael Alarcón Sierra
doaj  

Real‐World Effectiveness and Safety of a Tubeless Automated Insulin Delivery System With an Adaptive Control Algorithm (APGO) in Children and Adolescents With Type 1 Diabetes: A Multicentre Observational Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim Automated insulin delivery (AID) systems improve glycaemic outcomes in Type 1 diabetes; however, paediatric real‐world data on newly introduced tubeless AID systems remain limited. We aimed to provide the first clinical evaluation of the A8 TouchCare Nano AID system with the APGO algorithm in children and adolescents with Type 1 diabetes ...
Angela Zanfardino, Dario Iafusco, Giorgia Ippolito, Emanuele Miraglia del Giudice, Assunta Serena Rollato, Antonietta Chianese, Adele Figuccia, Sonia Toni, Annalisa Giulia Ferlito, Barbara Piccini   +9 more
wiley   +1 more source

Rubén Darío: Los desheredados de la suerte

Cuadernos del CILHA
Este artículo analiza la preocupación de Rubén Darío por los desheredados en la sociedad como ejemplo de su humanidad hacia los ancianos, los niños, la pobreza y hacia aquellos que tienen que enfrentar situaciones vitales difíciles. La compasión de Darío
Pablo Kraudy
doaj  

Chasing the perfida Albione: Anglo‐Italian productivity gap in the late 1930s

The Economic History Review, EarlyView.
Abstract This paper presents new estimates of Anglo‐Italian labour productivity levels in manufacturing in the late 1930s, derived using the standard single‐deflation approach. The findings confirm a substantial productivity gap between Italy and the United Kingdom at the aggregate level, alongside pronounced intersectoral heterogeneity.
Tancredi Salamone
wiley   +1 more source

Multi‐omics analyses reveal host–microbe interactions in atopic dermatitis and psoriasis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Atopic dermatitis (AD) and psoriasis (PSO) are chronic inflammatory skin diseases with complex host–microbe interactions. This study analysed skin samples from patients and healthy individuals using integrated microbial and transcriptomic profiling. Both diseases showed disrupted fungal–bacterial interactions and alterations in host immune responses ...
Ying Yang, Peter Olah, Alexander Salava, Jonathan Barker, Antti Lauerma, Björn Andersson, Nanna Fyhrquist, Bernhard Homey, Harri Alenius   +8 more
wiley   +1 more source

Darío y el simbolista Mallarmé, o deslecturas del hueco de la analogía

Revista Chuy
Dentro de las diversas corrientes artísticas que se incorporaron al modernismo sin excluirse mutuamente, destaca el simbolismo francés cuyo ingreso en la década de 1890 resultó crucial en la poesía hispanoamericana y en la de Rubén Darío.
Azusa Tanase
doaj  

Rubén Darío y Valle-Inclán: relaciones poéticas

Santiago, 2016
Rubén Darío revolucionó el verso de su época, fue el gran divulgador de una nueva forma de hacer literatura, a la que se sumó Valle-Inclán realizando esa misma transformación rubeniana en la prosa.
José Servera Baño
doaj  

Inflation in Theory and Practice: A Comprehensive Review of the Literature From the Great Inflation to the 2020s Surge

Journal of Economic Surveys, EarlyView.
ABSTRACT The post‐pandemic inflationary spike brought inflation back to the forefront of academic research. In the debate about the origin and nature of the 2020s inflation, economists have been divided into the following two main camps: the demand‐pull camp, which attributed inflation to excess demand and linked it to fiscal and monetary stimulus put ...
Vicente Ferreira
wiley   +1 more source