Results 51 to 60 of about 5,151 (200)

Systematic review and meta-analysis of iron therapy in anaemic adults without chronic kidney disease: updated and abridged Cochrane review [PDF]

open access: yes, 2016
AIMS: Anaemia is increasingly recognized as having an independent impact upon patient outcomes in cardiac disease. The role of novel iron therapies to treat anaemia is increasing.
Anker, SD   +5 more
core   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 228-240, January 2026.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan   +6 more
wiley   +1 more source

Use of erythropoiesis stimulating agents [PDF]

open access: yes, 2014
UNIFESP Hospital São Paulo Setor de HemodiáliseHospital Beneficência PortuguesaUFJF Serviço de Nefrologiacentro de pesquisa IMEPENUNIFESP, Hospital São Paulo Setor de ...
Abreu, Patricia Ferreira   +2 more
core   +3 more sources

CERA Detection and Stability in Blood Versus Urine

open access: yesDrug Testing and Analysis, Volume 18, Issue 1, Page 16-23, January 2026.
This study presents comparative data on CERA detection in serum and urine samples, highlighting adverse analytical findings (AAFs) in serum that were undetected in corresponding urine samples. This shift would significantly improve the efficiency and sensitivity of CERA detection in doping control, ensuring more effective doping control programs ...
Olivier Salamin   +4 more
wiley   +1 more source

USING OF LONG ACTION ERYTHROPOES STIMULATED AGENTS FOR TREATMENT OF ANEMIA IN PATIENTS WITH CHRONIC KIDNEY DISEASES V D ST

open access: yesУкраїнський Журнал Нефрології та Діалізу, 2014
 the article describes approaches to cost optimization of anemia treatment in CKD–VDst. patients by comparison of costs in phase correction and support treatment with long action ESA in patients on HD and HDF. Aims.
M. Kolesnyk   +4 more
doaj   +1 more source

Advanced Urologic Cancer Consensus Conference (AUC3) 2025: Expert consensus on the management of renal cell and urinary tract cancers

open access: yesCA: A Cancer Journal for Clinicians, Volume 76, Issue 1, January/February 2026.
Abstract The therapeutic landscape for renal cell carcinoma (RCC) and urinary tract cancer (UTC) has transformed dramatically, creating complexity in treatment selection and sequencing. The 2025 Advanced Urologic Cancer Consensus Conference was convened to establish evidence‐based expert consensus recommendations for optimal management.
Rana R. McKay   +53 more
wiley   +1 more source

An asymmetric tetrabody is a potent and efficacious agonist of the erythropoietin receptor in vitro and in vivo

open access: yesProtein Science, Volume 34, Issue 10, October 2025.
Abstract Erythropoietin (EPO) initiates EPO receptor (EPOR) signaling in hematopoietic cells by binding to an asymmetric EPOR dimer through two different sites. We engineered dimeric diabody‐Fc (Db‐Fc) fusion proteins that appeared to act as potent agonists of human EPOR in cell proliferation assays. However, detailed analysis of their oligomeric forms
Jarrett J. Adams   +15 more
wiley   +1 more source

Search of new pharmaceuticals on the basis of darbepoetin in the treatment of ischemic stroke: review of literature [PDF]

open access: yes, 2017
The article contains the analysis of medical and biological publications from the global database created by the National Centre for Biology Information (NCBI), an intramural biotechnological division of the US National Library of Medicine.
Gorbunova, N. S.   +4 more
core   +2 more sources

Comparison of Pharmacokinetic, Pharmacodynamic and Tolerability Profiles of CKD-11101, Darbepoetin Alfa (NESP®) Biosimilar, to Those of NESP® After a Single Subcutaneous or Intravenous Administration to Healthy Subjects

open access: yesDrug Design, Development and Therapy, 2021
Inseung Jeon,1,* Jaeseong Oh,1,* Yu-Kyung Kwon,2 Seo Hyun Yoon,1 Joo-Youn Cho,1 In-Jin Jang,1 Kyung-Sang Yu,1 SeungHwan Lee1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul ...
Jeon I   +7 more
doaj  

Darbepoetin alfa for treating chemotherapy-induced anemia in patients with a baseline hemoglobin level < 10 g/dL versus ≥10 g/dL: an exploratory analysis from a randomized, double-blind, active-controlled trial

open access: yesBMC Cancer, 2009
Background Several studies have shown that darbepoetin alfa, an erythropoiesis-stimulating agent (ESA), can reduce transfusions and increase hemoglobin (Hb) levels in patients with chemotherapy-induced anemia (CIA).
Vermorken Jan   +8 more
doaj   +1 more source

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