Darier disease: Current insights and challenges in pathogenesis and management
Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 5, Page 942-951, May 2025.Darier disease (DD) is characterized by the following: Disrupted Ca2+ gradients, impaired desmosomes, impaired keratinocyte differentiation, type 17 inflammation, DC and LC ↓, Th17 cells ↑. DD treatment: First line: keratinocyte focused and/or anti‐inflammatory. Second line: experimental approaches like specific targeting of the inflammatory infiltrate.
Monika Ettinger +8 more
wiley +1 more source
Comparative oncology: The paradigmatic example of canine and human mast cell neoplasms [PDF]
, 2019 In humans, advanced mast cell (MC) neoplasms are rare malignancies with a poor prognosis. Only a few preclinical models are available, and current treatment options are limited. In dogs, MC neoplasms are the most frequent malignant skin tumours.
Arock M. +13 more
core +1 more source
A Rare Clinical Presentation of Darier’s Disease
Case Reports in Dermatological Medicine, 2013 Darier’s disease, also known as keratosis follicularis or dyskeratosis follicularis, is a rare disorder of keratinization. It is an autosomal dominant genodermatosis with high penetrance and variable expressivity.
Mybera Ferizi +4 more
doaj +1 more source
VEGF-induced intracellular Ca2+ oscillations are down-regulated and do not stimulate angiogenesis in breast cancer-derived endothelial colony forming cells. [PDF]
, 2017 Endothelial colony forming cells (ECFCs) represent a population of truly endothelial precursors that promote the angiogenic switch in solid tumors, such as breast cancer (BC).
Biggiogera Marco +13 more
core +1 more source
Kaposi's varicelliform eruption in a patient with darier's disease: A rare case report
Clinical Dermatology ReviewDarier's disease is a rare autosomal dominant disorder, characterized clinically by the appearance of multiple, pruritic, discrete, and scaly papules affecting seborrheic areas coupled with palmar pits, nail changes, and mucosal involvement ...
Trishala Shirahatti, H Bangaru
doaj +1 more source
Calcium signaling in epithelium : Special focus on Hailey-Hailey and Darier diseases, neurofibromatosis 1 and transitional cell carcinoma [PDF]
, 2008 This study utilized normal and defective epithelial cell cultures and epidermal skin samples to examine intra- and intercellular calcium signaling. The main interests of this thesis were Hailey-Hailey disease (HHD), Darier disease (DD), neurofibromatosis
Leinonen, Pekka
core
Erythroderma: analysis of 247 cases [PDF]
, 1995 The profile of 247 patients with erythroderma during a 23 year period from January, 1962 through March, 1985, with a follow-up period ranging from 1 to 26 years were analysed.
Aoki, Valéria +5 more
core +4 more sources
Mixed Variant of Acrokeratosis verruciformis of Hopf: A rare entity [PDF]
, 2021 Acrokeratosis verruciformis of Hopf (AKV) is a rare autosomal dominant genodermatosis of unknown etiology. Here we present a case of a 20-year-female with multiple skin-colored flat papules over the dorsum of hands and feet interspersed with multiple ...
Abhay Vilas Deshmukh +3 more
core +1 more source
A dermatoglyphic investigation of selected skin disorders [PDF]
, 1994 This investigation involved the study of qualitative and quantitative digital and palmar traits in patients with various selected skin disorders and normal control subjects.
Blackwell, David
core
Solitary Mastocytoma in Pediatrics. Case Report and Literature Review
Revista Finlay, 2020 The mastocytoma is a genodermatosis of unknown etiology, so it is included in the group of rare or uncommon diseases; it usually appears in childhood or at birth.
Juan Carlos Yanes Macías +2 more
doaj +2 more sources