Results 51 to 60 of about 957 (153)

Mimicking Darier Disease In Vitro: A Human Epidermal Organoid Approach

Experimental Dermatology, Volume 34, Issue 12, December 2025.
ABSTRACT Darier disease (DD) is a rare genetic disorder caused by mutations in the ATP2A2 gene, resulting in calcium dysregulation and impaired keratinocyte adhesion. Due to the paucity of suitable models, understanding the molecular mechanisms of DD has been challenging.
Rishika Agarwal, Erika Parente, Simon M. Müller, Elisabeth A. Kappos, Tanja Dittmar, Michael Kunz, Roni P. Dodiuk‐Gad, Nisim Asayag, Johann E. Gudjonsson, Beda Mühleisen, Emmanuel Contassot, Alexander A. Navarini   +11 more
wiley   +1 more source

Darier Disease [PDF]

Mayo Clinic Proceedings, 2021
Tejesh S. Patel, Miguel Herrera-Martinez
openaire   +2 more sources

SEVERE OSTEOPOROSIS DUE TO SYSTEMIC MAST CELL DISEASE: SUCCESSFUL TREATMENT WITH INTERFERON ALPHA-2B [PDF]

, 2017
We describe a 33-yr-old man suffering from severe vertebral osteoporosis and urticaria pigmentosa due to systemic mast cell disease (SMCD). Because i.v.
BEYELER, C., DAHINDEN, C., GERBER, N. J., HUNZIKER, T., LEHMANN, T., LÄMMLE, B., OLAH, A. J., VOCK, P.   +7 more
core  

Defining the interactome of the pancreas‐specific SPCA2 isoform (SPCA2C) identifies unique links to store‐operated Ca2+ entry

The FEBS Journal, Volume 292, Issue 24, Page 6644-6669, December 2025.
A BioID screen identified interacting proteins for secretory pathway calcium (Ca2+) ATPase 2C (SPCA2C) and showed new links to store‐operated Ca2+ entry. Interactions between SPCA2C and Orai1 were confirmed, along with newly identified interactions with STIM1 and CCDC47.
Petra Samardzija, Melissa A. Fenech, Oneeb Hassan, Ryann Lang, McKenzie C. Carter, Stephanie Chen, Selina Shi, Rithwik Ramachandran, Peter B. Stathopulos, Christopher L. Pin   +9 more
wiley   +1 more source

ALA-PDT combined with 2940 nm ablative fractional Er:YAG laser for Darier's disease

Photodiagnosis and Photodynamic Therapy
Darier's disease is a rare, genetically determined dyskeratotic skin disorder. Although many conventional treatments have been reported, management of Darier's disease remains challenging.
Tingting Gao, Junyan Xiao, Na Pan, Fan Xia, Xianyu Zeng, Li Qin   +5 more
doaj   +1 more source

VEGF-induced intracellular Ca2+ oscillations are down-regulated and do not stimulate angiogenesis in breast cancer-derived endothelial colony forming cells. [PDF]

, 2017
Endothelial colony forming cells (ECFCs) represent a population of truly endothelial precursors that promote the angiogenic switch in solid tumors, such as breast cancer (BC).
Biggiogera Marco, Cattaneo Fabio, Guerra Germano, Khdar Dlzar Ali, Laforenza Umberto, Lodola, Francesco, Massa Margherita, Moccia Francesco., Poletto Valentina, Riccardi Alberto, Rosti Vittorio, Ruffinatti Federico Alessandro, Tancredi Richard, Zuccolo Estella   +13 more
core   +1 more source

Mosaic Darier's Disease: A Case of Unilateral Localized Type I Segmental Darier's Disease

Clinical Case Reports
Darier's disease (DD), also known as Darier‐White disease, is a rare autosomal dominant genodermatosis resulting from mutations in the ATP2A2 gene. It commonly manifests as keratotic papules or plaques in seborrheic areas and is often triggered by heat ...
Lina Al‐Soufi, Aya Marashli, Hamza Warda, Zuheir Al‐Shehabi   +3 more
doaj   +1 more source

A case study on the dermatoscopic findings of Darier's disease in skin type VI

Skin Health and Disease, 2023
We present dermatoscopic findings of long‐standing, untreated Darier's disease (DD) in skin type VI that differs from current findings in literature.
Samavia Khan, Banu Farabi, Alina Zufall, Anjelica Peacock, Kenneth Helmandollar, Kenneth Shulman, Bijan Safai   +6 more
doaj   +1 more source

An 11‐Month‐Old Infant With Unusual Diaper Dermatitis

JEADV Clinical Practice, EarlyView.
Majda Chaoui, Léo‐Paul Secco, Ifigenia Spanoudi‐Kitrimi   +2 more
wiley   +1 more source

Prevalence, Age of Onset, Age at Diagnosis, and Family History of Hidradenitis Suppurativa in Pediatric Populations: A Systematic Review and Meta‐Analysis

Pediatric Dermatology, Volume 42, Issue 6, Page 1142-1148, November/December 2025.
ABSTRACT Introduction Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterized by recurrent nodules and abscesses in intertriginous areas, ultimately resulting in scarring and formation of sinus tracts. HS significantly impacts quality of life and can also affect pediatric populations.
Grace Xiong, Mohamed Ali, Erfan Ghani Kakhki, Annie Xiong, Raed Alhusayen, David Croitoru, Cathryn Sibbald, Vincent Piguet, Ilya Mukovozov   +8 more
wiley   +1 more source