Results 101 to 110 of about 9,062,329 (360)

Putin’s Dark Ages [PDF]

open access: yes
Two decades before the war against Ukraine, a “special operation” was launched against Russian historical memory, aggressively reshaping the nation’s understanding of its history and identity.
Khapaeva, Dina
core   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Creep Characterization of Inconel 718 Lattice Metamaterials Manufactured by Laser Powder Bed Fusion

open access: yesAdvanced Engineering Materials, EarlyView., 2023
Herein, the creep characteristics of additively manufactured Inconel 718 metamaterials are investigated. The creep behavior of metamaterials and the effects of microstructural defects are assessed, and the microstructure defects are accurately captured using Kachanov's creep damage model.
Akash Singh Bhuwal   +5 more
wiley   +1 more source

E and S0 galaxies in the central part of the Coma cluster: Ages, metal abundances and dark matter [PDF]

open access: yes, 1999
Mean ages and metal abundances are estimated for the stellar populations in a sample of 115 E and S0 galaxies in the central 64'x70' of the Coma cluster. The estimates are based on the line indices Mg2, and Hbeta, and the mass-to-light ratios (M/L). Stellar population models from Vazdekis et al.
arxiv   +1 more source

The age dependence of galaxy clustering [PDF]

open access: yesMon.Not.Roy.Astron.Soc.378:777-784,2007, 2006
We construct mock galaxy catalogues to analyse clustering properties of a Lambda cold dark matter (LCDM) universe within a cosmological dark matter simulation of sufficient resolution to resolve structure down to the scale of dwarfs. We show that there is a strong age-clustering correlation for objects likely to host luminous galaxies, which includes ...
arxiv   +1 more source

The existence and detection of optically dark galaxies by 21cm surveys [PDF]

open access: yes, 2006
One explanation for the disparity between Cold Dark Matter (CDM) predictions of galaxy numbers and observations could be that there are numerous dark galaxies in the Universe.
Auld, R.   +4 more
core   +2 more sources

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

Revisit of cosmic age problem [PDF]

open access: yesPhys.Rev.D82:103006,2010, 2010
We investigate the cosmic age problem associated with 9 extremely old globular clusters in M31 galaxy and 1 very old high-$z$ quasar APM 08279 + 5255 at $z=3.91$. These 9 globular clusters have not been used to study the cosmic age problem in the previous literature. By evaluating the age of the universe in the $\Lambda$CDM model with the observational
arxiv   +1 more source

The Dark Ages of the Universe and hydrogen reionization [PDF]

open access: yes, 2014
One of the milestones in the cosmic history is the formation of the first luminous objects and Hydrogen reionization. The standard theory of cosmic structure formation predicts that the first generation of stars were born about a few hundred million ...
A. Natarajan, N. Yoshida
semanticscholar   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

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