Results 51 to 60 of about 120,890 (299)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Single Remote Sensing Image Dehazing Using Robust Light-Dark Prior
Remote Sensing, 2023 Haze, generated by floaters (semitransparent clouds, fog, snow, etc.) in the atmosphere, can significantly degrade the utilization of remote sensing images (RSIs).
Jin Ning +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Image Haze Removal Algorithm Using a Logarithmic Guide Filtering and Multi-Channel Prior
IEEE Access, 2021 In reality, the quality of an image is generally affected by haze. To obtain a well-quality image, removing haze is a hot issue on theory and application. This paper proposes a new algorithm to remove haze of hazy images.
Yuanyang Zou +3 more
doaj +1 more source
Improved reflection removal with dark channel prior
, 2021 This article proposed an idea that the quality of reflection removal can be improved by preprocess the input image with a dehaze method (which is dark channel prior in this paper).
openaire +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Efficient single image dehazing by modifying the dark channel prior
EURASIP Journal on Image and Video Processing, 2019 Outdoor images can be degraded due to the particles in the air that absorb and scatter light. The produced degradation generates contrast attenuation, blurring, and distortion in pixels, resulting in low visibility. These limit the efficiency of computer
Sebastián Salazar-Colores +3 more
doaj +1 more source
Blind Image Deblurring via a Novel Sparse Channel Prior
Mathematics, 2022 Blind image deblurring (BID) is a long-standing challenging problem in low-level image processing. To achieve visually pleasing results, it is of utmost importance to select good image priors. In this work, we develop the ratio of the dark channel prior (
Dayi Yang, Xiaojun Wu, Hefeng Yin
doaj +1 more source
FEBS Open Bio, EarlyView.This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili +2 more
wiley +1 more source