Results 61 to 70 of about 173,637 (267)

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

open access: yesAdvanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong   +11 more
wiley   +1 more source

Probe of Dark Galaxies via Disturbed/Lopsided Isolated Galaxies [PDF]

open access: yesProceedings of the International Astronomical Union, 2007
AbstractSearching for lopsided/interacting objects among 1500 isolated galaxies yields only eight strongly disturbed galaxies which may be explained as a result of their interaction with massive dark objects. We present results of spectral and photometric observations of these galaxies performed with the 6-m telescope that lead to significant ...
Karachentsev, Igor D.   +4 more
openaire   +2 more sources

Long‐Term Elevated CO2 Improves Soil Health and Rice Yields in Paddy Fields

open access: yesAdvanced Science, EarlyView.
Combining the two longest‐running rice free‐air CO2 enrichment experiments with a global data synthesis, this study demonstrates that long‐term elevated CO2 consistently enhances soil health. In rice paddies, this improvement sustains the CO2 fertilization effect over decades.
Fan Jiang   +22 more
wiley   +1 more source

From Sample to Mixed Reality: A Translational 3D MALDI Imaging Platform for Advanced 3D Spatial Omics Analysis of 3D Cell Culture Disease Models

open access: yesAdvanced Science, EarlyView.
A comprehensive technology platform enables high‐fidelity, volumetric MALDI imaging of 3D cell cultures by integrating custom embedding molds, a semi‐automated computational framework for 3D reconstruction, voxel‐instead of pixel‐based biomarker discovery, and immersive mixed reality data exploration.
Stefania Alexandra Iakab   +16 more
wiley   +1 more source

The Gut Commensal Butyricimonas Virosa Modulates Gut Microbiota‐Dependent Thiamine Metabolism and Attenuates Mouse Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
This study reveals that dietary stachyose enriches Butyricimonas virosa, effectively attenuating metabolic dysfunction‐associated steatotic liver disease (MASLD). Mechanistically, B. virosa enhances gut thiamine monophosphate synthesis, which elevates hepatic thiamine pyrophosphate levels.
Ningning He   +17 more
wiley   +1 more source

Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides

open access: yesAdvanced Science, EarlyView.
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das   +13 more
wiley   +1 more source

Polar Disk Galaxies as new way to study galaxy formation: the case of NGC4650A

open access: yes, 2010
NGC4650A is a polar disk galaxy: this is a peculiar object composed by a central spheroidal component, the host galaxy (HG), and an extended disk made up by gas, stars and dust, which orbits nearly perpendicular to the plane of the central galaxy.
Iodice, E.
core   +1 more source

Dark energy and dark matter in galaxy halos

open access: yesPhysics Letters B, 2006
7 pages, 1 figure, references added and discussion ...
openaire   +3 more sources

Tidal Debris Posing as Dark Galaxies [PDF]

open access: yesProceedings of the International Astronomical Union, 2007
AbstractDebris sent into the intergalactic medium during tidal collisions has received much attention as it can tell us about several fundamental properties of galaxies, in particular their missing mass, both in the form of cosmological Dark Matter and so-called Lost Baryons.High velocity encounters, which are common in clusters of galaxies, are able ...
Duc, Pierre-Alain   +2 more
openaire   +2 more sources

Multitarget Recognition of Flower Images Based on Lightweight Deep Neural Network and Transfer Learning

open access: yesAdvanced Intelligent Systems, EarlyView.
This article proposes a lightweight YOLOv4‐based detection model using MobileNetV3 or CSPDarknet53_tiny, achieving 30+ FPS and higher mAP. It also presents a ShuffleNet‐based classification model with transfer learning and GAN‐augmented images, improving generalization and accuracy.
Qingyang Liu, Yanrong Hu, Hongjiu Liu
wiley   +1 more source

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