Results 121 to 130 of about 213,451 (373)
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Dark matter haloes within clusters [PDF]
Monthly Notices of the Royal Astronomical Society, 1998 LaTeX MN style, 20 pages, 30 figures included + 1 colour ...
Joachim Stadel +5 more
openaire +3 more sources
The impact of baryonic discs on the shapes and profiles of self-interacting dark matter halos
, 2018 We employ isolated N-body simulations to study the response of self-interacting dark matter (SIDM) halos in the presence of the baryonic potentials. Dark matter self-interactions lead to kinematic thermalization in the inner halo, resulting in a tight ...
Creasey, Peter +5 more
core +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
The Astrophysical JournalThe dark matter halo properties, for example, mass, spin, and concentration, play a significant role in the formation and evolution of bars in disk galaxies.
Sandeep Kumar Kataria, Juntai Shen
doaj +1 more source
On the Mass Dependence of the Inner Slopes of Dark Matter Density Profiles
Open Astronomy, 2014 We study through a semi-analytic model how the inner slopes of relaxed ΛCDM dark matter halos with and without baryons depend on the halo mass. We find that the inner logarithmic density slope, α ≡ d log ρ/d log r, of dark matter halos with baryons has a
Del Popolo A.
doaj +1 more source
The halo model for cosmology: a pedagogical review
The Open Journal of Astrophysics, 2023 We present a pedagogical review of the halo model, a flexible framework that can describe the distribution of matter and its tracers on non-linear scales for both conventional and exotic cosmological models.
Marika Asgari +2 more
doaj +1 more source
Mapping stellar content to dark matter haloes – II. Halo mass is the main driver of galaxy quenching [PDF]
, 2015 We develop a simple yet comprehensive method to distinguish the underlying drivers of galaxy quenching, using the clustering and galaxy-galaxy lensing of red and blue galaxies in SDSS.
Y. Zu, R. Mandelbaum
semanticscholar +1 more source
On the assembly history of dark matter haloes [PDF]
Monthly Notices of the Royal Astronomical Society, 2007 15 pages, 13 figures (with 2 new), accepted by ...
Li, Y +3 more
openaire +4 more sources
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source