Results 131 to 140 of about 437,676 (389)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

The halo model for cosmology: a pedagogical review

open access: yesThe Open Journal of Astrophysics, 2023
We present a pedagogical review of the halo model, a flexible framework that can describe the distribution of matter and its tracers on non-linear scales for both conventional and exotic cosmological models.
Marika Asgari   +2 more
doaj   +1 more source

A dark matter scaling relation from mirror dark matter [PDF]

open access: yes, 2013
Mirror dark matter, and other similar dissipative dark matter candidates, need an energy source to stabilize dark matter halos in spiral galaxies. It has been suggested previously that ordinary supernovae can potentially supply the required energy.
Foot, R.
core   +2 more sources

Germline variants in CDKN2A wild‐type melanoma prone families

open access: yesMolecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen   +5 more
wiley   +1 more source

Modeling the Galaxy Distribution in Clusters using Halo Cores

open access: yesThe Open Journal of Astrophysics, 2023
The galaxy distribution in dark matter-dominated halos is expected to approximately trace the details of the underlying dark matter substructure. In this paper we introduce halo "core-tracking" as a way to efficiently follow the small-scale substructure ...
Danila Korytov   +7 more
doaj   +1 more source

Dark Matter Mini-halo around the Compact Objects: the Formation, Evolution and Possible Contribution to the Cosmic Ray Electrons/Positrons

open access: yes, 2011
Dark matter particles may be captured by a star and then thermalized in the star's core. At the end of its life a massive star collapses suddenly and a compact object is formed. The dark matter particles redistribute accordingly.
Chang, Jin   +3 more
core   +1 more source

Neutrino Constraints on the Dark Matter Total Annihilation Cross Section [PDF]

open access: yes, 2007
In the indirect detection of dark matter through its annihilation products, the signals depend on the square of the dark matter density, making precise knowledge of the distribution of dark matter in the Universe critical for robust predictions.
A. Klypin   +5 more
core   +2 more sources

Mapping stellar content to dark matter haloes – II. Halo mass is the main driver of galaxy quenching [PDF]

open access: yes, 2015
We develop a simple yet comprehensive method to distinguish the underlying drivers of galaxy quenching, using the clustering and galaxy-galaxy lensing of red and blue galaxies in SDSS.
Y. Zu, R. Mandelbaum
semanticscholar   +1 more source

Dark matter haloes within clusters [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 1998
LaTeX MN style, 20 pages, 30 figures included + 1 colour ...
Joachim Stadel   +5 more
openaire   +3 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

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