Results 181 to 190 of about 117,029 (345)

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

Polarized equatorial emission and hot spots around black holes with a dark matter halo

open access: yesEuropean Physical Journal C: Particles and Fields
We study linear polarization of the accretion disks around black holes with a dark matter halo. The interaction of the black hole with the dark matter is modeled by considering an exact solution to the Einstein equations which describe a superposition of
Tsanimir Angelov   +4 more
doaj   +1 more source

Laser‐Based Sculpturing of Embedded Ultrathin Metal‐Oxide Nanopores for Enhanced Biomolecular Sensing

open access: yesAdvanced Functional Materials, EarlyView.
Controlled laser‐drilling of embedded HfO2 membranes creates three layer nanopores with Gaussian‐shaped cavities sculptured in the supporting layers. These embedded solid‐state nanopores slow DNA translocation by 12‐fold compared to SiNx pores, enabling high‐resolution, label‐free detection of short DNAs, RNAs, and proteins.
Jostine Joby   +4 more
wiley   +1 more source

The “Little Dark Dot”: Evidence for Self-interacting Dark Matter in the Strong Lens SDSS J0946+1006?

open access: yesThe Astrophysical Journal
Previous studies, based on precise modeling of a gravitationally lensing image, have identified what may be an extremely compact, dark perturber in the well-known lensing system SDSS J0946+1006 (the “Jackpot”).
Shubo Li   +15 more
doaj   +1 more source

An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio   +8 more
wiley   +1 more source

Three‐dimensional Antimony Sulfide Based Flat Optics

open access: yesAdvanced Functional Materials, EarlyView.
This work presents the development of a grayscale electron beam lithography (g‐EBL) method for fabricating antimony trisulfide (Sb2S3) nanostructures with customizable 3D profiles. The refractive index of g‐EBL patterned Sb2S3 is determined based on the synergy of genetic algorithm and transfer matrix method.
Wei Wang   +18 more
wiley   +1 more source

C-19 and Hot, Wide Star Streams

open access: yesThe Astrophysical Journal
The C-19 star stream has the abundance characteristics of an unusually metal-poor globular cluster but kinematically is uncharacteristically hot and wide for a cluster stream, having a line-of-sight velocity dispersion of 7  ±  2 km s ^−1 and a 1 σ width
Raymond G. Carlberg   +7 more
doaj   +1 more source

Cosmological zoom-in simulation of fuzzy dark matter down to z = 0: tidal evolution of subhaloes in a Milky Way-sized halo [PDF]

open access: gold
Hei Yin Jowett Chan   +5 more
openalex   +1 more source

Dwarf galaxies in multistate scalar field dark matter halos [PDF]

open access: green, 2015
L. A. Martinez-Medina   +2 more
openalex   +1 more source

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