Results 81 to 90 of about 117,029 (345)

Why are some galaxy disks extremely thin?

open access: yes, 2012
Some low surface brightness galaxies are known to have extremely thin stellar disks with the vertical to planar axes ratio 0.1 or less, often referred to as superthin disks.
Banerjee, Arunima, Jog, Chanda J.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

The interaction of dark matter cusp with the baryon component in disk galaxies

open access: yes, 2012
In this paper we examine the effect of the formation and evolution of the disk galaxy on the distribution of dark halo matter. We have made simulations of isolated dark matter (DM) halo and two component (DM + baryons).
A. A. Dutton   +44 more
core   +1 more source

Infall Caustics in Dark Matter Halos? [PDF]

open access: yesThe Astrophysical Journal, 2008
We show that most particle and subhalo orbits in simulated cosmological cold dark matter halos are surprisingly regular and periodic: The phase space structure of the outer halo regions shares some of the properties of the classical self-similar secondary infall model. Some of the outer branches are clearly visible in the radial velocity - radius plane
Diemand, J., Kuhlen, M.
openaire   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Halo-Independent Comparison of Direct Dark Matter Detection Data

open access: yesAdvances in High Energy Physics, 2014
We review the halo-independent formalism that allows comparing data from different direct dark matter detection experiments without making assumptions on the properties of the dark matter halo.
Eugenio Del Nobile
doaj   +1 more source

Elliptical galaxies with rapidly decreasing velocity dispersion profiles: NMAGIC models and dark halo parameter estimates for NGC 4494

open access: yes, 2013
NGC 4494 is one of several intermediate-luminosity elliptical galaxies inferred to have an unusually diffuse dark matter halo. We use the chi^2-made-to-measure particle code NMAGIC to construct axisymmetric models of NGC 4494 from photometric and various
Arnaboldi, Magda   +4 more
core   +1 more source

Dark matter heats up in dwarf galaxies [PDF]

open access: yes, 2019
Gravitational potential fluctuations driven by bursty star formation can kinematically 'heat up' dark matter at the centres of dwarf galaxies. A key prediction of such models is that, at a fixed dark matter halo mass, dwarfs with a higher stellar mass ...
Read, J. I., Steger, P., Walker, M. G.
core   +2 more sources

Cold Dark Matter Halos Must Burn [PDF]

open access: yes, 2006
High-quality optical rotation curves for a sample of low-luminosity spirals evidence that the dark halos around galaxies are inconsistent with the output of proper CDM simulations. In fact, dark halos enveloping stellar disks are structures with approximately a constant density out to the optical edges.
Salucci, Paolo, Borriello A.
openaire   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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