Results 81 to 90 of about 234,039 (316)
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
On the Spatial Distribution of Dark Matter Halos [PDF]
The Astrophysical Journal, 1998 We study the spatial distribution of dark matter halos in the Universe in terms of their number density contrast, related to the underlying dark matter fluctuation via a non-local and non-linear bias random field. The description of the matter dynamics is simplified by adopting the `truncated' Zel'dovich approximation to obtain both analytical results ...
CATELAN P. +2 more
openaire +4 more sources
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source
The halo model for cosmology: a pedagogical review
The Open Journal of Astrophysics, 2023 We present a pedagogical review of the halo model, a flexible framework that can describe the distribution of matter and its tracers on non-linear scales for both conventional and exotic cosmological models.
Marika Asgari +2 more
doaj +1 more source
Black Hole Space-time In Dark Matter Halo [PDF]
, 2018 For the first time, we obtain the analytical form of black hole space-time metric in dark matter halo for the stationary situation. Using the relation between the rotation velocity (in the equatorial plane) and the spherical symmetric space-time metric coefficient, we obtain the space-time metric for pure dark matter.
arxiv +1 more source
Germline variants in CDKN2A wild‐type melanoma prone families
Molecular Oncology, EarlyView.Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen +5 more
wiley +1 more source
Modeling the Galaxy Distribution in Clusters using Halo Cores
The Open Journal of Astrophysics, 2023 The galaxy distribution in dark matter-dominated halos is expected to approximately trace the details of the underlying dark matter substructure. In this paper we introduce halo "core-tracking" as a way to efficiently follow the small-scale substructure ...
Danila Korytov +7 more
doaj +1 more source
Dark matter haloes within clusters [PDF]
Monthly Notices of the Royal Astronomical Society, 1998 LaTeX MN style, 20 pages, 30 figures included + 1 colour ...
Joachim Stadel +5 more
openaire +3 more sources
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
The Astrophysical JournalThe dark matter halo properties, for example, mass, spin, and concentration, play a significant role in the formation and evolution of bars in disk galaxies.
Sandeep Kumar Kataria, Juntai Shen
doaj +1 more source