Results 41 to 50 of about 859,999 (292)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Controls on Nutrient Cycling in Estuarine Mangrove Lake Sediments
Journal of Marine Science and Engineering, 2021 We estimated the net exchange of nitrogen and phosphorus species using core incubations under light and dark conditions in estuarine lakes that are the aquatic interface between the freshwater Everglades and marine Florida Bay.
Michael S. Owens +5 more
doaj +1 more source
Cosmological constant and gravitational theory on D-brane
, 2003 In a toy model we derive the gravitational equation on a self-gravitating curved D-brane. The effective theory on the brane is drastically changed from the ordinal Einstein equation.
A. Riess +24 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
A Mamba U-Net Model for Reconstruction of Extremely Dark RGGB Images
SensorsCurrently, most images captured by high-pixel devices such as mobile phones, camcorders, and drones are in RGGB format. However, image quality in extremely dark scenes often needs improvement.
Yiyao Huang +7 more
doaj +1 more source
Soil moisture dynamics under two rainfall frequency treatments drive early spring CO2 gas exchange of lichen-dominated biocrusts in central Spain [PDF]
PeerJ, 2018 Background Biocrusts, communities dominated by mosses, lichens, cyanobacteria, and other microorganisms, largely affect the carbon cycle of drylands. As poikilohydric organisms, their activity time is often limited to short hydration events.
Selina Baldauf +3 more
doaj +2 more sources
, 2009 The hypothesis of an `invisible' axion was made by Misha Shifman and others, approximately thirty years ago. It has turned out to be an unusually fruitful idea, crossing boundaries between particle physics, astrophysics and cosmology.
Kolb E. W., P. SIKIVIE, Pethik C. J.
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Estimation of the net production of moss community at Langhovde, East Antarctica
Antarctic Record, 1992 Field measurements of net photosynthesis and dark respiration (CO_2 exchange) of moss colonies were carried out at Langhovde, East Antarctica from 9 to 17 January 1988. Each colony growing at the Yukidori Valley, Langhovde was composed of Grimmia lawiana,
Yoshio Ino
doaj +1 more source