Results 61 to 70 of about 859,999 (292)

Reseña/Review (Morozov, Evgeny, "The net delusion: the dark side of Internet freedom", Nueva York: Public Affairs, ISBN: 16103910, 448 págs., 2011)

Revista Teknokultura, 2012
Reseña/Review (Morozov, Evgeny, "The net delusion: the dark side of Internet freedom", Nueva York: Public Affairs,  ISBN: 16103910, 448 págs., 2011)
César Rendueles
doaj   +2 more sources

The Electrosphere of Macroscopic "Quark Nuclei": A Source for Diffuse MeV Emissions from Dark Matter

, 2010
Using a Thomas-Fermi model, we calculate the structure of the electrosphere of the quark antimatter nuggets postulated to comprise much of the dark matter.
A. R. Zhitnitsky, Ariel R. Zhitnitsky, E. W. Kolb, Kyle Lawson, L. D. Landau, Michael McNeil Forbes   +5 more
core   +1 more source

Baryons and Dark Matter from the Late Decay of a Supersymmetric Condensate [PDF]

, 1995
The possibility that both the baryon asymmetry and dark matter arise from the late decay of a population of supersymmetric particles is considered. If the decay takes place below the LSP freeze out temperature, a nonthermal distribution of LSPs results ...
Affleck, Barr, Bottino, Chivukula, Cline, Cohen, Coughlan, Dimopolous, Dimopoulos, Dine, Dine, Dress, Ellis, Ellis, Ellis, Ellis, Ellis, Ellis, Griest, Grisaru, Kaplan, Kernan, Khlopov, Kolb, Krauss, Lazarides, Lindley, Lyth, McDonald, Mizuta, Mollerach, Nanopoulos, Nanopoulos, Nussinov, Olive, Rajagopal, Reno, Roszkowski, Roszkowski, Scott Thomas, Seiberg, Smith, Walker   +42 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

A Pipeline Neural Network for Low-Light Image Enhancement

IEEE Access, 2019
Low-light image enhancement is an important challenge in computer vision. Most of the low-light images taken in low-light conditions usually look noisy and dark, which makes it more difficult for subsequent computer vision tasks.
Yanhui Guo, Xue Ke, Jie Ma, Jun Zhang
doaj   +1 more source

Horn-Coupled, Commercially-Fabricated Aluminum Lumped-Element Kinetic Inductance Detectors for Millimeter Wavelengths [PDF]

, 2014
We discuss the design, fabrication, and testing of prototype horn-coupled, lumped-element kinetic inductance detectors (LEKIDs) designed for cosmic microwave background (CMB) studies.
Ade, P., Araujo, D., Bradford, K., Cantor, R., Che, G., Day, P., Doyle, S., Flanigan, D., Johnson, B. R., Jones, G., Leduc, H., Limon, M., Luu, V., Mauskopf, P., McCarrick, H., Miller, A., Mroczkowski, T., Tucker, C., Zmuidzinas, J.   +18 more
core   +4 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source