Cognitive Behavioural Therapy and Light Dark Therapy for Maternal Postpartum Insomnia Symptoms: Protocol of a Parallel-Group Randomised Controlled Efficacy Trial [PDF]
Frontiers in Global Women's Health, 2021 Background: Symptoms of insomnia are common in new mothers and have been associated with a range of negative maternal and child outcomes. Despite this, interventions to improve maternal postpartum sleep remain scarce.
Sumedha Verma +5 more
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The Dark Side of Dopamine Agonist Therapy in Prolactinoma Management [PDF]
AACE Clinical Case Reports, 2017 Sonia Ananthakrishnan, MD
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Vasopressor Therapy and the Brain: Dark Side of the Moon [PDF]
Frontiers in Medicine, 2020 Sepsis, a leading cause of morbidity and mortality, is caused by a deregulated host response to pathogens, and subsequent life-threatening organ dysfunctions.
Nicholas Heming +8 more
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Photodynamic Therapy in 2020: Lights in the Darkness [PDF]
SKIN The Journal of Cutaneous Medicine, 2020 Photodynamic therapy (PDT) is an integral treatment modality for treating the entire process of photodamage, based on what is understood about the pathogenesis of actinic keratosis and the consequences from treating only visible spots and not the underlying disease.
Neal Bhatia
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Related Article from Photodynamic Therapy: A Light in the Darkness?
Clinical Cancer Research, 2023 Abstract Photodynamic therapy (PDT) is used to treat localized premalignant or early malignant disease. This study reports the enhanced, systemic antitumor immune response from PDT, suggesting that it may have a potential role as a therapy to address both local and disseminated disease.
Alexander Lin, Stephen M. Hahn
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Eliminate dark side from antiplatelet therapy [PDF]
Blood, 2014 In this issue of Blood , Stefanini and colleagues report a new way to regulate platelet function. Mice expressing a talin-1 mutant (W359A) that disrupts its binding to the NPxY motif in β3 were protected from experimental thrombosis without undermining hemostasis by decelerating αIIbβ3 ...
Yoshiaki Tomiyama
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Oral Nirmatrelvir/Ritonavir Therapy for COVID-19: The Dawn in the Dark? [PDF]
Antibiotics, 2022 Nirmatrelvir/ritonavir (Paxlovid™) is an effective and safe antiviral drug that inhibits the main protease (Mpro), 3CL protease, of SARS-CoV-2. A reduction in COVID-19-related hospitalization or death was observed in patients treated with nirmatrelvir ...
Yuan-Pin Hung +6 more
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Photodynamic Therapy for Granuloma Annulare: More than a Shot in the Dark [PDF]
Dermatology, 2008 <i>Background:</i> Granuloma annulare (GA) is a benign granulomatous and inflammatory skin disorder. The pathogenesis remains enigmatic and convincingly effective treatment options are not available. Inspired by a report showing photodynamic therapy (PDT) to be effective in a single patient with GA, we sought to evaluate this benefit in a ...
Peter Weisenseel +5 more
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Successful Treatment of Facial Multiple Melanocytic Nevus-Like Dark Macules Caused by Severe Acne Vulgaris by a Single Session of Intense Pulsed Light Treatment [PDF]
Clinical, Cosmetic and Investigational DermatologyJinxiang Yang,1,2,* Jinwen Shen,1,2,* Yuwei Kong,1,2,* Lei Wang,1,2 Zhirong Yao,1,2 Jianying Liang,1,2 Xia Yu1,2 1Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People’s Republic of ...
Yang J +6 more
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The Dark Side of Mast Cell–Targeted Therapy in Prostate Cancer [PDF]
Cancer Research, 2012 Abstract Tumor development requires accomplices among white blood cells. Other than macrophages, mast cells have been observed to support the outgrowth of certain neoplasias because of their proangiogenic properties. In some tumor settings, however, mast cells may have a protective role, exerted by their proinflammatory mediators.
Paola Pittoni, Mario P. Colombo
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