Results 121 to 130 of about 308,632 (278)
RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav+5 more
wiley +1 more source
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang+6 more
wiley +1 more source
Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang+8 more
wiley +1 more source
Adjustable Plasmonic Core–Shell Nanoparticles for Personalized Color Vision Correction
This study introduces a personalized solution for correcting color vision deficiency (CVD) by embedding tunable core‐shell metal nanoparticles—a common nanotechnology—into contact lenses. By customizing the nanoparticles’ optical properties to filter specific wavelengths, these lenses address individual visual impairments, enhancing color ...
Hyeonah Lee+4 more
wiley +1 more source
Key Trends and Insights in Smart Polymeric Skin Wearable Patches
Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez+2 more
wiley +1 more source
AAV-mediated RLBP1 gene therapy improves the rate of dark adaptation in Rlbp1 knockout mice
Recessive mutations in RLBP1 cause a form of retinitis pigmentosa in which the retina, before its degeneration leads to blindness, abnormally slowly recovers sensitivity after exposure to light.
Vivian W Choi+24 more
doaj
Suppression of dark current radiation in step‐and‐shoot intensity modulated radiation therapy by the initial pulse‐forming network [PDF]
Chee‐Wai Cheng, Indra J. Das, A Ndlovu
openalex +1 more source
3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht+5 more
wiley +1 more source