Design and synthesis of water-solube chlorin derivatives as photosensitizer for photodynamic therapy
Results in ChemistryAs a new tumor therapy with low side effects, photodynamic therapy (PDT) uses a certain wavelength of light to excite the photosensitizer enriched in the tumor site to produce biological and chemical toxic ROS, thereby killing tumor cells and inhibiting ...
Yu-Qi Yang +8 more
doaj
1206 Profiling the dark genome of tumours provides new potential therapies for cancer patients [PDF]
Nathaniel J. Davies +21 more
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Advanced Functional Materials, EarlyView.The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai +9 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari +11 more
wiley +1 more source
Investigation on the phenytoin sodium channel-blocker effect in PDT of MDA MB 231 breast cancer using a positively charged PS. [PDF]
Sci RepEsfahani H, Hosseinzadeh R, Khorsandi K.
europepmc +1 more source
CAR T Cell Therapy for Solid Tumors: Bright Future or Dark Reality? [PDF]
, 2020 Jessica Wagner +3 more
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Fast Neutron Detector Based on Hybrid 2D Perovskite Thin Films
Advanced Functional Materials, EarlyView.This work presents the direct detection of fast neutrons using flexible hybrid 2D perovskite (PEA2PbBr4) thin‐film detectors. Thanks to their high low‐Z elements content and good charge transport, these materials enable efficient neutron detection. The thin film configuration allowed the operation at low voltage, and offer scalability, flexibility, and
Ilaria Fratelli +11 more
wiley +1 more source
A Case of Surgery for a Giant Popliteal Venous Aneurysm Positive for Heparin-Induced Thrombocytopenia Antibodies with Repeated Acute Pulmonary Embolism. [PDF]
Ann Vasc DisTomita S +6 more
europepmc +1 more source
M85. LIGHT-DARK AND ACTIVITY RHYTHM THERAPY TO IMPROVE SLEEP IN SCHIZOPHRENIA SPECTRUM DISORDERS: EXPERT CONSENSUS, INTERVENTION DEVELOPMENT AND FEASIBILITY TESTING [PDF]
, 2020 Sophie Faulkner +3 more
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Transient Stiffness Patterning in Hydrogels Driven by Dissipative Mechanochemical Coupling
Advanced Functional Materials, EarlyView.Force‐induced disulfide bond rupture in a polymer‐based hydrogel, coupled with chemical or electrochemical reoxidation, leads to the transient modulation of the hydrogel's stiffness properties. High spatiotemporal control is achieved by this dissipative process, enabling the development of out‐of‐equilibrium stiffness patterns and transient, dose ...
Roberto Baretta +2 more
wiley +1 more source