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Photodynamic Therapy: A Light in the Darkness?
Clinical Cancer Research, 2009Abstract Photodynamic therapy (PDT) is used to treat localized premalignant or early malignant disease. This study reports the enhanced, systemic antitumor immune response from PDT, suggesting that it may have a potential role as a therapy to address both local and disseminated disease.
Alexander, Lin, Stephen M, Hahn
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Dark therapy for mania: a pilot study
Bipolar Disorders, 2005Background: Recent findings suggest that extended bed rest and darkness could stabilize mood swings in rapid cycling bipolar patients.Method: We exposed 16 bipolar inpatients affected by a manic episode to a regimen of 14 h of enforced darkness from 6 p.m. to 8 a.m. each night for three consecutive days [dark therapy (DT)].
Barbini B +7 more
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The Dark Side of Targeted Therapy
European Urology, 2011Renal cell carcinoma (RCC) is a relatively rare malignancy from a global perspective. Yearly around the world, approximately 200 000 new cases of RCC are diagnosed and approximately 100 000 patients die of their disease [1]. Management of patients with localized and locally advanced RCC has focused mainly on surgical therapy, as effective adjuvant ...
Jose A. Karam, Christopher G. Wood
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The Dark Side of Implantable Cardioverter Defibrillator Therapy
Cardiology, 2013No abstract ...
John, Somberg, Janos, Molnar
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Dark chocolate: consumption for pleasure or therapy?
Journal of Thrombosis and Thrombolysis, 2008Traditional chocolate is derived from the cocoa bean, which is one of the most concentrated sources of flavanols, a subgroup of the natural antioxidant plant compounds called flavonoids. Accumulating evidence from the past 10 years demonstrates that moderate consumption of chocolate, especially dark chocolate, may exert protective effects against the ...
LIPPI, Giuseppe +5 more
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Dark Urine Related to Metronidazole Therapy
JAMA: The Journal of the American Medical Association, 1971To the Editor.— We had the opportunity to observe a patient with amebic dysentery who, while undergoing treatment with metronidazole (Flagyl), 750 mg by mouth three times a day, passed dark-brown urine. Dark urine persisted during the fiveday course of therapy and it promptly subsided on termination of the drug.
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Eliminate dark side from antiplatelet therapy
Blood, 2014In this issue of Blood , Stefanini and colleagues report a new way to regulate platelet function. Mice expressing a talin-1 mutant (W359A) that disrupts its binding to the NPxY motif in β3 were protected from experimental thrombosis without undermining hemostasis by decelerating αIIbβ3 ...
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Resisting loneliness' dark pit: a narrative therapy approach
Tizard Learning Disability Review, 2013PurposePeople with learning disabilities want and value friendships and close, intimate, or romantic relationships. However, many people with learning disabilities are socially and emotionally lonely. The purpose of this paper is to describe a novel intervention, using a narrative therapy based group approach, which aimed to ameliorate the negative ...
James Stacey, Adrian Edwards
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