Results 41 to 50 of about 688,109 (238)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Enterprise Systems and Threats [PDF]

Journal of Systemics, Cybernetics and Informatics, 2021
The scenario included a medium-sized international company. The guidelines were to select and include three enterprise systems that were based on databases, one cloud-based and one that was not SQL-based.
Risa Blair
doaj  

The Anonymity of the Dark Web: A Survey

IEEE Access, 2022
The dark web is a section of the Internet that is not accessible to search engines and requires an anonymizing browser called Tor. Its hidden network and anonymity pave the way for illegal activities and help cybercriminals to execute well-planned ...
Javeriah Saleem, Rafiqul Islam, Muhammad Ashad Kabir   +2 more
doaj   +1 more source

A kinematic classification of the cosmic web [PDF]

, 2012
A new approach for the classification of the cosmic web is presented. In extension of the previous work of Hahn et al. (2007) and Forero-Romero et al.
Forero-Romero, Jaime E., Gottlöber, Stefan, Hoffman, Yehuda, Knebe, Alexander, Libeskind, Noam I., Metuki, Ofer, Yepes, Gustavo   +6 more
core   +3 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Gif Lectures on direct detection of Dark Matter

, 2010
These notes cover some of the topics associated with direct detection of dark matter at an introductory level. The general principles of dark matter search are summarized.
Alford, Banerjee, Banerjee, Bertone, Feng, Finch, Gilson, Gosset, Han, Han, Ichimura, Ionel Lazanu, Klingenberg, Lazanu, Lazanu, Lazanu, Lindhard, Lu, Madsen, Paulucci, Perez-Garcia, Perillo Isaac, Perillo Isaac, Posselt, Price, Saito, Sigmund, Sorina Lazanu, Sumner, Takahashi, Wen, Wilk, Witten, Ziegler   +33 more
core   +2 more sources

PASTA‐ELN: Simplifying Research Data Management for Experimental Materials Science

Advanced Engineering Materials, EarlyView.
Research data management faces ongoing hurdles as many ELNs remain complex and restrictive. PASTA‐ELN offers an open‐source, cross‐platform solution that prioritizes simplicity, offline access, and user control. Its in tuitive folder structure, modular Python add‐ons, and open formats enable seamless documentation, FAIR data practices, and easy ...
S. Brinckmann, G. Winkens, R. Schwaiger
wiley   +1 more source

Extended percolation analysis of the cosmic web

, 2018
Aims. We develop an extended percolation method to allow the comparison of geometrical properties of the real cosmic web with the simulated dark matter web for an ensemble of over- and under-density systems. Methods. We scan density fields of dark matter
Einasto, J., Einasto, M., Liivamägi, L. J., Suhhonenko, I.   +3 more
core   +1 more source

Tidal stirring and the origin of dwarf spheroidals in the Local Group [PDF]

, 2000
N-Body/SPH simulations are used to study the evolution of dwarf irregular galaxies (dIrrs) entering the dark matter halo of the Milky Way or M31 on plunging orbits.
Ben Moore, de Blok W. J. G., Fabio Governato, George Lake, Irwin M., James Wadsley, Joachim Stadel, Lacey C., Lake G., Lucio Mayer, Monica Colpi, Thomas Quinn, Zwaan M. A.   +12 more
core   +2 more sources

Enhanced Strength and Corrosion Resistance of Ti‐13Nb‐12Ta‐10Zr‐4Sn Alloy by Aging Treatment

Advanced Engineering Materials, EarlyView.
This work systematically investigates the effect of aging treatment on mechanical properties and corrosion behavior of vacuum arc‐melted Ti‐13Nb‐12Ta‐10Zr‐4Sn alloy. Owing to the increased α″ martensite, strength and corrosion resistance were significantly enhanced by aging treatment.
Yuhua Li, Rong Zhao, Qian Zhang, Haojie Wang, Yujing Liu, Lai‐Chang Zhang   +5 more
wiley   +1 more source