Results 191 to 200 of about 152,438 (313)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Is the FEO Food-Entrainable? Reexamining the Classic Fred Stephan Experiment Using Canonical-Clock-Less <i>Period 1/2/3</i> Triple Knockout Mice. [PDF]

J Biol Rhythms
Taufique SKT, Ehichioya DE, Farah S, Shen M, Yamazaki S.   +4 more
europepmc   +1 more source

CONRAD's Heart of Darkness [PDF]

, 2013
Fazzino, Anna Maria
core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Metabolic imaging of <i>Fragilariopsis cylindrus</i> in polar night conditions using full-field optical transmission tomography (FFOTT). [PDF]

Biomed Opt Express
Joli N, Boccara C, Bailleul B, Bowler C, Boccara M.   +4 more
europepmc   +1 more source

Reactions to Light and Darkness

, 1903
REACTIONS TO LIGHT AND DARKNESS Reactions to Light and Darkness (14) (-
Hall, Granville Stanley Theodate L. Smith
core  

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Evaluation of Quality Changes in Huajiao Seed Oil During Different Storage Conditions. [PDF]

Foods
Peng X, Fu B, Liu H, Fang C, Kan J.
europepmc   +1 more source

THE LIGHT OF DARKNESS? THE DARKNESS THAT OVERSHADOWS THE LIGHT?: THE MOTIF OF DARKNESS IN MACBETH, WAITING FOR GODOT AND HEART OF DARKNESS

In Samuel Becket's Waiting for Godot, it is 'darkness' that is waited for. Estragon and Vladimirwait for Godot in the same place every day until darkness falls. They can't leave or stop waitingfor Godot before darkness falls. When evening comes, darkness
Görmez, Merve Betül
core  

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source