Results 101 to 110 of about 354,705 (299)
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Phoneys and the dash man: the hypnotic voice of J. D. Salinger
, 2010 Salinger called himself 'a dash man', quintessentially a short story writer, but I'm not so sure about that. The Catcher in the Rye is an overblown short story, but the Glass family saga is something else. The dash is a breathless narrative momentum that
Goodall, Jane
core +1 more source
Proceedings of the 9th ACM Multimedia Systems Conference, 2018 6 pages, submitted to ACM MMSys'18 (dataset track)
Anatoliy Zabrovskiy +2 more
openaire +3 more sources
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
, 2020 This thesis proposes that an alternative to the existing cable television system could be created using the MPEG-DASH protocol (Dynamic Adaptive Streaming over HTTP) and other readily available internet technologies including web servers and content ...
Bresnahan, Brian Patrick
core +3 more sources
Bio-ProtocolReactive oxygen species (ROS) are central regulators of plant development and stress responses, with hydrogen peroxide (H2O2) acting as a key signaling molecule whose spatial distribution determines adaptive versus damaging outcomes.
Mario Fenech, Vitor Amorim-Silva
doaj +1 more source
Arctic lakes ice break-up timing for 2000 - 2013 [PDF]
This dataset includes break-up start and break-up end dates for 13 300 lakes larger than 1 km2 in five study areas in the Arctic. The dates were derived using time-series of daily surface reflectance data at 250m spatial resolution acquired by the ...
Dash, Jadunandan +2 more
core +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
JSES Reviews, Reports, and TechniquesBackground: Patient-reported outcome measures (PROMs) rely on individual interpretation of questions and recall ability, which limits their standardization.
Nathan Miner, MS +7 more
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source