Results 1 to 10 of about 26,722,291 (305)
Data driven selection of consensus docking pipelines for structure based hit identification [PDF]
npj Drug DiscoveryStructure-based virtual screening (SBVS) is a cornerstone of computer-aided drug design, yet its success depends on selecting a combination of docking tools, scoring function (SF), and ranking strategies.
Hamza Agha +6 more
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Land, 2023 The variability in soil properties and crop yield can be overcome by adoption of smart farming practices through interpolation and mapping of spatial variability patterns.
Zainab Haroon +8 more
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Incremental Adaptive Control of a Class of Nonlinear Nonaffine Systems
Complexity, 2022 As a class of familiar nonlinear systems, nonaffine systems are frequently encountered in practical applications. Currently, in the context of learning control, there is a lack of research results about such general class of nonlinear systems, especially
Yizhao Zhan +3 more
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Radiomics for characterization of the glioma immune microenvironment
npj Precision Oncology, 2023 Increasing evidence suggests that besides mutational and molecular alterations, the immune component of the tumor microenvironment also substantially impacts tumor behavior and complicates treatment response, particularly to immunotherapies. Although the
Nastaran Khalili +9 more
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Data-Driven Nonsmooth Optimization [PDF]
SIAM Journal on Optimization, 2020 In this work, we consider methods for solving large-scale optimization problems with a possibly nonsmooth objective function. The key idea is to first specify a class of optimization algorithms using a generic iterative scheme involving only linear operations and applications of proximal operators.
Sebastian Banert +4 more
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Mesh-Free Surrogate Models for Structural Mechanic FEM Simulation: A Comparative Study of Approaches
Applied Sciences, 2021 The technical world of today fundamentally relies on structural analysis in the form of design and structural mechanic simulations. A traditional and robust simulation method is the physics-based finite element method (FEM) simulation. FEM simulations in
Johannes G. Hoffer +3 more
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BMC Bioinformatics, 2020 Background Gene fusion events are significant sources of somatic variation across adult and pediatric cancers and are some of the most clinically-effective therapeutic targets, yet low consensus of RNA-Seq fusion prediction algorithms makes therapeutic ...
Krutika S. Gaonkar +15 more
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IEEE Access, 2023 Fully-supervised object detection and instance segmentation models have accomplished notable results on large-scale computer vision benchmark datasets. However, fully-supervised machine learning algorithms’ performances are immensely dependent on ...
Cathaoir Agnew +5 more
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On data-driven Saak transform [PDF]
Journal of Visual Communication and Image Representation, 2018 Being motivated by the multilayer RECOS (REctified-COrrelations on a Sphere) transform, we develop a data-driven Saak (Subspace approximation with augmented kernels) transform in this work. The Saak transform consists of three steps: 1) building the optimal linear subspace approximation with orthonormal bases using the second-order statistics of input ...
C.-C. Jay Kuo, Yueru Chen
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ETNA - Electronic Transactions on Numerical Analysis, 2022 We present a framework enabling variational data assimilation for gradient flows in general metric spaces, based on the minimizing movement (or Jordan-Kinderlehrer-Otto) approximation scheme. After discussing stability properties in the most general case, we specialise to the space of probability measures endowed with the Wasserstein distance.
Pietschmann, Jan-Frederik +1 more
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