Results 171 to 180 of about 19,419,888 (317)

Replication Data for: Fundamental scaling laws of water-window X-rays from free electron-driven van der Waals structures

Replication Data for: Fundamental scaling laws of water-window X-rays from free electron-driven van der Waals ...
Pramanik, Nikhil
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

The IZA/Fable Data Consumption Indicator

Fable Data obtains card payment data directly from various financial institutions across Europe. The ingested data is enriched by proprietary models from Fable Data and is then homogenised and productised to generate a single pan-European dataset that’s ...
Martinez, Anoop Bindra, Askitas, Nikos, Cereda, Fabio Saia   +2 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A data-driven computational methodology for assessing ventricular ablation procedures. [PDF]

Biomech Model Mechanobiol
Caruso Lombardi F, Crispino A, Nguyen BL, Galea N, Loppini A, Filippi S, Viola F, Gizzi A.   +7 more
europepmc   +1 more source

Optimizing outcomes: Professional perspectives on data-driven marketing mastery

This technological phase completely discovers the vibrant domain name of data-driven advertising diving right into its meaning, significance, as well as present landscape with a certain concentrate on expert system (artificial intelligence (AI ...
Prasad A., Paul T., Rastogi T., Benedetto F., Tyagi U.   +4 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

microntology: a lightweight, data-driven controlled vocabulary to describe earth's microbial habitats. [PDF]

Bioinformatics
Fullam A, Prasoodanan PKV, Kuhn M, Bork P, Schmidt TSB.   +4 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Genetic Associations of Parkinson's Disease Clinical, Pathological, and Data-Driven Subtypes. [PDF]

Genes (Basel)
Negida A, Abouelmagd ME, Hamed BM, Hawas Y, Dziri A, Negida Y, Berman BD, Barrett MJ.   +7 more
europepmc   +1 more source